4-Methoxy-3-nitrobenzotrifluoride is employed in the pharmaceutical industry as a building block for synthesizing antitumor and anti-inflammatory active compounds, and serves as a key intermediate in materials science for the synthesis of liquid crystals and organic optoelectronic materials. Industrially, it is supplied in bulk packaging.

Catalog

4-METHOXY-3-NITROBENZOTRIFLUORIDE Bulk Supply for Industrial Use

China Factory Direct
	CAS number	394-25-2
	Product name	4-METHOXY-3-NITROBENZOTRIFLUORIDE
	Stock	Stock readily available; annual supply capacity exceeding 1,000 tons.
	Grade	Pharmaceutical GradeMaterial GradeSpecialty Grade
	Packaging	25KG/bag500KG/bag1000KG/bag
	Sample	Test Samples Available (Click to Request Samples)
	COA	View COA
	Price	Get Quote
	Supply Type	Bulk / Contract manufacturing / OEM
	Shipping	FCL / LCL available
	Payment Terms	Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
	Manufacturer	Greenrock Chemical(China Factory)

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CAS No:394-25-2

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Documents We Provide for 4-METHOXY-3-NITROBENZOTRIFLUORIDE

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart

Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.

Bulk 4-METHOXY-3-NITROBENZOTRIFLUORIDE Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of 4-METHOXY-3-NITROBENZOTRIFLUORIDE

Industry	Application	Process
Pesticides	Key intermediate for synthesizing novel herbicides (e.g., triclopyr-type herbicides)	Used to prepare triclopyr via condensation and cyclization reactions with salicylic acid derivatives
Pharmaceuticals	Structural building block for synthesizing antitumor and anti-inflammatory compounds	Serves as an aryl substituent in coupling reactions (e.g., Suzuki, Heck) to construct target molecular frameworks
Materials Science	Intermediate for synthesizing liquid crystal and organic optoelectronic materials	Modifies liquid crystalline behavior or tunes HOMO/LUMO energy levels through nitro group reduction and functionalization of methoxy or trifluoromethyl groups

Manufacturing Quality Control of 4-METHOXY-3-NITROBENZOTRIFLUORIDE

Detection Item	Common Analytical Method	Method Overview
Assay (Purity)	HPLC-UV	Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection.
Related Substances	HPLC-UV	Separation and quantification of impurities based on retention time and UV response relative to the main peak.
Residual Solvents	GC-FID	Detection and quantification of volatile organic solvents using gas chromatography with flame ionization detection.
Water Content	Karl Fischer Titration	Volumetric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol solvent system.
Heavy Metals	ICP-OES	Multi-element detection after acid digestion, based on atomic emission intensities at characteristic wavelengths.
Chloride Impurity	Ion Chromatography	Separation and quantification of chloride anions using suppressed conductivity detection.
Sulfated Ash	Gravimetric Analysis	Measurement of non-volatile inorganic residue after high-temperature incineration and weighing.
Melting Point	Capillary Melting Point Apparatus	Determination of solid-to-liquid phase transition temperature using controlled heating and visual observation.
Appearance	Visual Inspection	Assessment of physical state, color, and clarity against defined standards under controlled lighting.
Specific Optical Rotation	Polarimetry	Measurement of rotation angle of plane-polarized light induced by chiral compounds in solution.
Particle Size Distribution	Laser Diffraction	Analysis of scattered laser light intensity patterns to calculate size distribution of solid particles in suspension.
pH of Aqueous Suspension	pH Meter	Measurement of hydrogen ion activity in a standardized aqueous slurry using calibrated glass electrode.

Technical Specifications of 4-METHOXY-3-NITROBENZOTRIFLUORIDE

Test Item	Specification
Appearance	Yellow solid
Purity	>=98.0% (GC-MS)
Total Impurities	<=2.0%
Single Impurity	<=0.5%
Melting Point	65-69°C
Water Content (KF)	<=0.5%
Identification (NMR)	Consistent with structure
Heavy Metals	<=10 ppm
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of 4-METHOXY-3-NITROBENZOTRIFLUORIDE

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NMR Spectra of 4-METHOXY-3-NITROBENZOTRIFLUORIDE

Safety Information of 4-METHOXY-3-NITROBENZOTRIFLUORIDE

Pictograms
Signal Word	Danger
Safety Data Sheet

Packaging of 4-METHOXY-3-NITROBENZOTRIFLUORIDE

We have a diverse range of chemicals in stock. Available in Bagged goods (25 kg.),Big bags (500 kg.), Big bags (1000 kg.).

Industrial 4-METHOXY-3-NITROBENZOTRIFLUORIDE Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

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