China Factory Direct
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| CAS number | 394-31-0 |
| Product name | 5-Hydroxyanthranilic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in the synthesis of the antidepressant paroxetine | Serves as a starting material or key building block for constructing the benzodioxan ring system via diazotization, coupling, and reduction reactions |
| Pharmaceutical Industry | Intermediate in the synthesis of anticancer and anti-inflammatory drugs | Undergoes amidation, esterification, or cyclization reactions via its amino and carboxyl functional groups to construct drug molecular scaffolds |
| Dye Industry | Production of azo dyes and functional pigments | Converted to diazonium salts via diazotization, followed by coupling with appropriate components to synthesize dyes with specific hues |
| Organic Synthesis | Synthesis of 2-substituted-3-amino-4(1H)-quinolone derivatives | Acts as a cyclization precursor in condensation and ring-closure reactions with reagents such as malonic acid derivatives |
| Research Reagents | Synthesis of fluorescent probes and metal ion indicators | Modified with specific fluorophores via coordination of its hydroxyl and amino groups for selective metal ion detection |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | By measuring the infrared absorption spectrum of the sample and comparing it with the standard spectrum, the characteristic functional groups (such as —OH, —NH₂, —COOH) and molecular structure of 2-aminophenol-5-hydroxybenzoic acid can be confirmed. |
| Ultraviolet-Visible Spectrophotometry (UV-Vis) | Use the characteristic absorption peak at specific wavelengths (e.g., about 240–300 nm) for qualitative identification. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column, an appropriate ratio of water-organic solvent (e.g., methanol or acetonitrile) as the mobile phase, and a UV detector (typically at 254 nm or 280 nm) to quantitatively analyze the main component content. It has high sensitivity and good repeatability. |
| Acid-Base Titration | Utilizing the acidity of the carboxyl group, titrate with a standard sodium hydroxide solution, and determine the endpoint using phenolphthalein or potentiometric method. Suitable for rough content determination. | |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Separate and detect possible synthetic by-products or degradation products using gradient elution or isocratic elution procedures. The impurity content is usually calculated by area normalization or by the main component self-control method with correction factor. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight, and measure the mass percentage loss due to moisture or volatile components. |
| Residue on Ignition | High-Temperature Ignition Method | Ignite the sample at high temperature (usually 700–800°C) and weigh the residual inorganic material to assess the content of inorganic impurities. |
| Heavy Metals | Thioacetamide Method (Colorimetry) or Atomic Absorption Spectrometry (AAS) | Determine the content of heavy metals such as lead, cadmium, mercury, and arsenic by reacting with thioacetamide to form colored precipitates for visual colorimetric analysis, or by using AAS for precise measurement. |
| pH Value | pH Meter Measurement | Prepare a solution of a certain concentration (e.g., 1% w/v) and measure its pH value using a calibrated pH meter, reflecting the free acid/alkali state. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range using a melting point apparatus. It serves as an auxiliary indicator for purity and identity confirmation (literature melting point is approximately 200–205°C, decomposition). |
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 175–179 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.