China Factory Direct
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| CAS number | 395-05-1 |
| Product name | 3-FLUOROMANDELIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Synthetic intermediate for active pharmaceutical ingredients (APIs), including chiral drugs, cardiovascular agents, and antidepressants | Serves as a chiral building block in asymmetric synthesis and esterification, or as a precursor for constructing phenylglycine-based structures |
| Agrochemicals | Intermediate for synthesizing agrochemicals, including fluorinated insecticides and herbicides | Introduces fluorinated aromatic rings to enhance compound stability and biological activity; commonly employed in condensation and functional group transformation reactions |
| Materials Science | Functional modifier in the synthesis of liquid crystal materials and polymer monomers | Leverages fluorine atom characteristics to tune dielectric constant or surface properties; typically applied in polymerization or molecular design |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities (e.g., 3-fluoro-mandelaldehyde, 3-fluorobenzoic acid) via gradient HPLC with diode-array detection and relative response factor correction. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., ethyl acetate, methanol, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration based on the reaction of iodine with water in anhydrous pyridine/methanol medium to determine trace moisture. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after microwave-assisted acid digestion, with detection at sub-ppt levels. |
| Optical Rotation | [α]D | Measurement of specific rotation using a digital polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by controlled heating of crystalline sample; deviation from literature value (74–76 °C) indicates impurity or polymorphic variation. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Ignition at 700–800 °C followed by weighing to determine inorganic ash content as sulfate or metal salt residues. |
| pH (1% w/v aqueous suspension) | Potentiometric pH Measurement | Direct measurement using calibrated pH electrode in aqueous suspension; reflects acidic character and potential hydrolysis products. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to assess bulk handling and dissolution behavior relevant to downstream processing. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens (e.g., E. coli, S. aureus) per Ph. Eur. 5.1.4. |
| Stereochemical Purity (Enantiomeric Excess) | Chiral HPLC | Separation on chiral stationary phase (e.g., Chiralpak AD-H) with UV detection to quantify (R)- vs (S)-enantiomer ratio and calculate ee%. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.