Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 39514-19-7 |
| Product name | Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antiallergic drugs (e.g., epinastine) | Organic synthesis, typically involving multistep reactions to construct the piperidine ring structure |
| Pharmaceuticals | Preparation of compounds with antihistaminic activity | Introduction of specific functional groups via alkylation, esterification, and related reactions |
| Chemical Research | Laboratory reagent for developing novel drug molecules | Use as a core scaffold in catalytic reactions or structural modifications |
Manufacturing Quality Control of Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
| Test Item | Common Analytical Method | Method Overview |
|---|---|---|
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | A reverse-phase C18 column is used with a mobile phase of methanol-water or acetonitrile-water. A UV detector (e.g., 254 nm) is employed for detection. The content of the main component is quantitatively analyzed by comparing the retention time and peak area with those of the reference standard. This method effectively separates impurities and is the most commonly used for purity assessment. |
| Impurity Testing | HPLC - Normalization Method for Impurity Peak Area | Under identical HPLC conditions, the areas of all impurity peaks in the sample are detected and summed to calculate the total impurity content. It can identify and quantify potential synthetic byproducts or degradation products, complying with pharmacopoeia requirements (e.g., ICH Q6A). |
| Residual Solvents | Gas Chromatography (GC) | A capillary column (e.g., DB-624) is used with headspace or direct injection methods to detect residual organic solvents from the reaction (e.g., ethanol, ether, dichloromethane). This complies with the ICH Q3C guideline. |
| Moisture Content | Karl Fischer Titration | The moisture content in the sample is determined through chemical titration. This method is suitable for compounds sensitive to moisture and ensures product stability and storage safety. |
| Melting Point Determination | Micro Melting Point Apparatus | The melting behavior of the sample is observed during heating to determine the melting range. It is used to initially confirm the purity and structural characteristics of the substance. A deviation from the standard melting point may indicate the presence of impurities or isomers. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Characteristic absorption peaks (e.g., C=O, C-O-C, C-N) are used to verify molecular structure. It is used to confirm the presence of specific functional groups and assist in authenticating the compound. |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR / ¹³C NMR | Provides information about the chemical environment of hydrogen and carbon atoms in the molecule. It is used to confirm structural integrity, stereochemistry, and the presence of isomers or structural defects. It is often considered the gold standard for structural confirmation. |
| Mass Spectrometry (MS) | Electrospray Ionization Mass Spectrometry (ESI-MS) or Electron Impact Mass Spectrometry (EI-MS) | Used to determine molecular weight and fragment ions to confirm the molecular formula (e.g., [M+H]⁺ or [M]⁺). It helps determine whether the sample is the target compound and if any byproducts are present. |
Technical Specifications of Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
Safety Information of Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate
Industrial Ethyl 1-benzyl-3-oxopiperidine-4-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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