Isonipecotamide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 39546-32-2 |
| Product name | Isonipecotamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Isonipecotamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Isonipecotamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Isonipecotamide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antiviral agents (e.g., HCV NS5A inhibitors) and central nervous system drugs | Introduces the piperidine ring structure into drug molecules via amide bond coupling or cyclization reactions |
| Agrochemicals | Structural modification unit for novel insecticides and fungicides | Functionalizes heterocyclic compounds to enhance target-binding affinity and metabolic stability |
| Materials Science | Ligand or crosslinker in functional polymer and organic optoelectronic material synthesis | Copolymerizes with diacids/anhydrides via condensation reactions, or serves as a ligand in metal complexes for OLED emissive layer doping |
Manufacturing Quality Control of Isonipecotamide
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with reference spectra to confirm the presence of characteristic functional groups (e.g., amide C=O, N-H) in the molecule, used for structural confirmation. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Use NMR technology to analyze chemical shifts, integration areas, and coupling constants of hydrogen atoms in the sample. Compare with standard spectra to verify the structure of piperidine-4-carboxamide. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ a reversed-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-water or methanol-buffer system) under isocratic or gradient elution. Quantify the main component using a UV detector (typically at 210–230 nm), offering high sensitivity and good reproducibility. |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Use similar or optimized chromatographic conditions as in the assay to separate and detect potential process impurities, degradation products, etc. Impurity levels are controlled using area normalization or a main component self-reference method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | In accordance with ICH Q3C guidelines, use headspace or direct injection to separate residual solvents (e.g., methanol, dichloromethane, ethanol) on a capillary column, with detection by a Flame Ionization Detector (FID). |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved. Calculate the percentage weight loss to assess moisture and volatile content. |
| Melting Point | Capillary Melting Point Determination | Pack the sample into a capillary tube and observe the temperature range from initial melting to complete melting under a controlled heating rate. Used as an auxiliary indicator of purity and identity. |
| pH (if in solution) | pH Meter Method | Prepare a solution of defined concentration (e.g., 1% w/v) in water and measure its acidity or alkalinity using a calibrated pH meter to detect potential acidic or basic impurities. |
| Heavy Metals | Thioacetamide Method or ICP-MS | After charring according to pharmacopoeial general chapters, perform colorimetric detection using a chromogenic reagent (thioacetamide method), or use Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to precisely determine total or individual elemental impurities such as lead, cadmium, mercury, and arsenic. |
Technical Specifications of Isonipecotamide
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Isonipecotamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Isonipecotamide
Packaging of Isonipecotamide
Industrial Isonipecotamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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