2-Nitrobenzyl bromide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3958-60-9 |
| Product name | 2-Nitrobenzyl bromide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Nitrobenzyl bromide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Nitrobenzyl bromide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Nitrobenzyl bromide
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as a precursor in the synthesis of antitumor agents (e.g., chlorambucil derivatives) and antimicrobial agents | Prepared via multi-step reactions including nitration and bromination; 2-nitrobenzyl bromide serves as a key benzylic bromination intermediate in nucleophilic substitution or palladium-catalyzed coupling reactions |
| Agrochemical Intermediates | Applied in the synthesis of novel insecticides and plant growth regulators (e.g., nitrobenzyl-containing pyrethroid derivatives) | Active molecular frameworks are constructed through reactions such as amination, reduction, or cyclization; the bromine atom provides a highly reactive site for subsequent functional group transformations |
| Organic Synthesis Reagents | A bifunctional building block enabling selective introduction of nitro and bromo groups at the benzylic position, employed in constructing complex aromatic heterocyclic compounds | Commonly used in alkylation reactions under phase-transfer catalysis, Heck coupling, Suzuki coupling, and nucleophilic addition/substitution reactions with organometallic reagents (e.g., Grignard reagents, organolithium reagents) |
Manufacturing Quality Control of 2-Nitrobenzyl bromide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Volatile organic impurities are vaporized in headspace vial and quantified by GC-FID using external calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Acid Value | Acid-Base Titration (NaOH standard solution) | Neutralization of acidic impurities (e.g., HBr, bromoacetic acid) with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals after acid digestion by measuring absorbance of ground-state atoms at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using anion-exchange column and conductivity detection. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities (e.g., 2-nitrobenzyl alcohol, 2-nitrotoluene) using reverse-phase C18 column and UV absorbance. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or foreign matter against established reference standards. |
| Bulk Density | Graduated Cylinder Method (ASTM D1895) | Mass per unit volume measured by pouring sample into a calibrated cylinder and recording settled volume. |
| Loss on Drying (LOD) | Gravimetric Analysis (105 C, 2 h) | Weight loss upon drying under specified temperature and time, indicating volatile content including residual solvents and moisture. |
| Residue on Ignition | Sulfated Ash Test (USP <281>) | Inorganic residue mass determined after high-temperature ignition following sulfuric acid treatment to convert organics to volatile species. |
Technical Specifications of 2-Nitrobenzyl bromide
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Nitrobenzyl bromide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Nitrobenzyl bromide
Packaging of 2-Nitrobenzyl bromide
Industrial 2-Nitrobenzyl bromide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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