(R)-(-)-alpha-Methoxyphenylacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3966-32-3 |
| Product name | (R)-(-)-alpha-Methoxyphenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-(-)-alpha-Methoxyphenylacetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-(-)-alpha-Methoxyphenylacetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-(-)-alpha-Methoxyphenylacetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral resolving agent for preparing optically pure enantiomers of chiral drugs (e.g., non-steroidal anti-inflammatory drugs such as ibuprofen and naproxen) | Forms diastereomeric salts with racemic amines, followed by separation via crystallization |
| Pharmaceuticals | Chiral auxiliary in the asymmetric synthesis of side chains for β-lactam antibiotics (e.g., carbapenems) | Introduced as a chiral auxiliary, then hydrolytically cleaved after multi-step reactions |
| Fine Chemicals | Synthetic intermediate for chiral liquid crystal materials and chiral catalysts | Chiral center constructed through esterification, halogenation, coupling, and other reactions to prepare BINOL derivatives or chiral phosphine ligands |
Manufacturing Quality Control of (R)-(-)-alpha-Methoxyphenylacetic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with Chiral Column | Separation and quantification using a chiral stationary phase and UV detection at 210-230 nm |
| Enantiomeric Excess (ee) | Chiral GC or Chiral HPLC | Direct separation of (R)- and (S)-enantiomers followed by peak area comparison |
| Water Content | Karl Fischer Titration | Electrochemical titration based on the reaction of iodine with water in pyridine/methanol medium |
| Residual Solvents | Gas Chromatography (GC) with FID | Volatile organic impurities separated on a polar capillary column and detected by flame ionization |
| Heavy Metals | ICP-OES | Quantification of Pb, Cd, Hg, As, and other metals after acid digestion and plasma emission spectroscopy |
| Chloride Impurity | Ion Chromatography (IC) | Anion exchange separation followed by suppressed conductivity detection |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of inorganic residue after sulfuric acid treatment |
| Optical Rotation | [alpha]D Measurement | Measurement of plane-polarized light rotation in solution at 20 C using sodium D-line (589 nm) |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate |
| Related Substances | HPLC with UV Detection | Separation on reversed-phase C18 column; detection at 210-230 nm to identify and quantify structural analogs |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue after ignition at 600-700 C in a muffle furnace |
Technical Specifications of (R)-(-)-alpha-Methoxyphenylacetic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Optical Rotation | -151.0 to -145.0 deg (c=1, in CHCl3) |
| Melting Point | 72.0 to 76.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-(-)-alpha-Methoxyphenylacetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-(-)-alpha-Methoxyphenylacetic acid
Safety Information of (R)-(-)-alpha-Methoxyphenylacetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-(-)-alpha-Methoxyphenylacetic acid
Industrial (R)-(-)-alpha-Methoxyphenylacetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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