(S)-2-Benzylsuccinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 3972-36-9 |
| Product name | (S)-2-Benzylsuccinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-2-Benzylsuccinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-2-Benzylsuccinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-2-Benzylsuccinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of angiotensin-converting enzyme (ACE) inhibitors, such as benazepril | Employed as a chiral building block to construct the diazabicyclic core structure of benazepril via acyl chloride formation, amination, and cyclization |
| Chiral Resolving Agents | Used for chiral resolution of racemates, particularly amines and alcohols | Forms diastereomeric salts with racemic amines, enabling crystallization-based separation via solubility differences |
| Organic Synthesis | Used as a chiral auxiliary or ligand precursor in asymmetric catalytic reactions | Derivatized into chiral phosphine or sulfoximine ligands for palladium-catalyzed asymmetric allylic substitution reactions |
Manufacturing Quality Control of (S)-2-Benzylsuccinic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies S-2-benzylsuccinic acid by reversed-phase HPLC with UV detection at 210 nm, using external standard calibration. |
| Related Substances | HPLC-DAD | Detects and quantifies structurally related impurities using HPLC with diode array detection and peak area comparison against reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., toluene, ethyl acetate) by gas chromatography with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated electrochemically or added reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after combustion with sulfuric acid treatment and high-temperature incineration to constant weight. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Identifies purity and identity by observing temperature range of solid-to-liquid phase transition under controlled heating. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic residue after ignition at 700-800 C without sulfuric acid pretreatment. |
| Microbial Limits | Membrane Filtration | Tests for total aerobic microbial count and absence of specified pathogens per pharmacopeial compendia using filtration and agar culture. |
Technical Specifications of (S)-2-Benzylsuccinic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Optical Rotation | -23.0 to -19.0 deg (c=1, in methanol) |
| Melting Point | 148 to 152 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-2-Benzylsuccinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-2-Benzylsuccinic acid
Packaging of (S)-2-Benzylsuccinic acid
Industrial (S)-2-Benzylsuccinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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