China Factory Direct
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| CAS number | 398-23-2 |
| Product name | 4,4'-Difluorobiphenyl |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Organic Synthesis | Synthesis of pharmaceutical intermediates | Introducing fluorine atoms into biphenyl structures via electrophilic substitution |
| Pharmaceutical Industry | Preparation of antitumor and antiviral agents | Serving as a key intermediate in multistep synthesis |
| Pesticide Industry | Synthesis of novel pesticide compounds | Used to prepare compounds with high insecticidal activity |
| Materials Science | Production of high-performance polymer materials | Employed as a monomer or crosslinking agent in the synthesis of specialty polymers |
| Analytical Chemistry | Preparation of reference standards | Used as a reference material in gas chromatography or mass spectrometry analysis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Separation and quantification of volatile organic solvents by equilibrium partitioning into headspace gas phase prior to GC analysis. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Atomization and excitation of metals in argon plasma; quantification via element-specific emission line intensity. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of anions on an ion-exchange column followed by quantitative detection based on electrical conductivity changes. |
| Acid-Base Impurities | Acid-Base Potentiometric Titration | Titration with standardized NaOH or HCl solution; endpoint determined by pH inflection point using a glass electrode. |
| Non-Volatile Residue | Gravimetric Analysis (Evaporation and Weighing) | Evaporation of a weighed sample under controlled conditions followed by drying and weighing of residual solids. |
| Melting Point | Capillary Melting Point Apparatus | Thermal observation of solid-to-liquid phase transition using calibrated capillary tube method per USP/Ph. Eur. guidelines. |
| Appearance | Visual Inspection (against white/black background) | Subjective assessment of color and clarity in a transparent container under controlled daylight-equivalent illumination. |
| UV Absorbance (at 280 nm) | UV-Visible Spectrophotometry | Measurement of absorbance at specified wavelength to detect conjugated impurities or degradation products. |
| Specific Optical Rotation | Polarimetry | Determination of rotation angle of plane-polarized light caused by chiral impurities or enantiomeric contaminants. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Analysis of angular scattering pattern of laser light passed through dispersed sample to calculate size distribution. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by GC-MS) |
| Melting Point | 67–69 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.