China Factory Direct
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| CAS number | 39825-33-7 |
| Product name | L-Alanine Isopropyl Ester Hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | L-Alanine chiral building block for synthesizing antiviral agents (e.g., favipiravir derivatives) and peptide-based therapeutics | Amidation with carboxylic acid derivatives, promoted by a base (e.g., DIPEA), in aprotic polar solvents (e.g., DMF or THF); the hydrochloride salt form facilitates crystallization, purification, and storage |
| Agrochemical Intermediates | Chiral auxiliary for synthesizing high-efficacy, low-toxicity chiral insecticides (e.g., pyrethroid derivatives) | Chiral side-chain construction via reductive amination with aldehydes/ketones or alkylation with alkyl halides under low-temperature conditions; the hydrochloride salt enhances reaction selectivity and yield |
| Personal Care Ingredients | Skin conditioning agent and penetration enhancer to improve transdermal delivery of active ingredients | Formulated with amino acid derivatives in mild aqueous systems (pH 4–6), leveraging its zwitterionic nature to modulate stratum corneum lipid fluidity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (L-Alanine Isopropyl Ester Hydrochloride) | Acid-Base Titration | Quantifies active compound by titration with standardized NaOH using bromocresol green indicator; endpoint corresponds to neutralization of HCl salt. |
| Water Content | Karl Fischer Titration | Measures water via iodine-sulfur dioxide reaction in methanol-based reagent; coulometric or volumetric mode provides precise moisture quantification. |
| Residual Solvents (Isopropanol, Ethyl Acetate) | Gas Chromatography (GC) with FID | Separates and quantifies volatile solvents using capillary column and flame ionization detection against calibrated standards. |
| Heavy Metals | ICP-OES | Digests sample in acid matrix and measures trace metal concentrations (e.g., Pb, Cd, Ni) via atomic emission at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration with AgNO3 | Determines chloride ions by titration with silver nitrate using silver electrode; inflection point indicates stoichiometric AgCl formation. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral L-alanine derivative in solution using sodium D-line light; confirms enantiomeric purity and identity. |
| Related Substances | HPLC with UV Detection | Separates and quantifies impurities (e.g., free L-alanine, diastereomers, hydrolysis products) on reversed-phase C18 column with UV detection at 205 nm. |
| pH of Aqueous Solution | pH Meter Measurement | Determines acidity of 1% w/v aqueous solution using calibrated pH electrode; reflects residual acidity and salt stability. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing; indicates inorganic contaminants or counterions. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid material against standard white background under controlled lighting; detects discoloration or particulates. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which crystalline solid transitions to liquid; verifies identity and purity based on sharp, defined melting behavior. |
| Microbial Limits | Membrane Filtration and Plate Count | Detects and enumerates aerobic microorganisms (bacteria, molds, yeasts) by filtration, culture on TSA/SDA, and colony counting per pharmacopeial guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128°C - 132°C |
| Optical Rotation | +12.5° to +14.5° (c=1, 6N HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.