China Factory Direct
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| CAS number | 39876-39-6 |
| Product name | 8-FLUORO-2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a synthetic intermediate in the preparation of biologically active fluorinated heterocyclic compounds, such as potential 5-HT receptor modulators or antidepressant drug candidates | Multi-step organic synthesis, typically involving Bischler–Napieralski or Pictet–Spengler reactions to construct the pyridoindole scaffold, followed by fluorination or functional group transformation to introduce fluorine |
| Chemical Research | Applied to investigate structure–activity relationships (SAR) and pharmacokinetic properties of fluorinated heterocyclic compounds | Laboratory-scale organic synthesis and structural modification, combined with high-throughput screening for biological activity assessment |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength, comparing peak area to calibrated standard. |
| Related Substances | HPLC-DAD or HPLC-MS | Detects and quantifies structurally related impurities by retention time and spectral matching against reference standards or thresholds. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection against certified standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine-sulfur dioxide reaction stoichiometry. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Hg, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature incineration and weighing of the cooled crucible. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation. |
| Optical Rotation | Polarimetry | Measures specific rotation of chiral compound in solution using plane-polarized light and calibrated scale. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension by measuring angular variation in laser light scattering. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determines acidity/basicity of a defined suspension using calibrated glass electrode and pH meter. |
| Microbial Contamination | Membrane Filtration and Plate Count | Detects and enumerates viable aerobic microorganisms by filtration, membrane transfer, and colony formation on nutrient agar. |
| Test Item | Specification |
|---|---|
| Appearance | Gray solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.