China Factory Direct
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| CAS number | 399-72-4 |
| Product name | 5-Fluoro-2-methylindole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of antitumor drug intermediates | Used as a key intermediate for constructing fluorinated indole compounds; employed in coupling or nucleophilic substitution reactions |
| Pharmaceutical R&D | Synthesis of antidepressant drug candidates | Enables introduction of functional groups via palladium-catalyzed cross-coupling reactions to prepare bioactive derivatives |
| Agrochemical Chemistry | Structural optimization of insecticides/fungicides | Serves as a heterocyclic scaffold for designing novel fluorinated agrochemical molecules to enhance metabolic stability and target selectivity |
| Organic Synthesis | Research on fluorinated indole compounds | Used to construct polysubstituted indole ring systems; participates in Friedel–Crafts alkylation, N-functionalization, and related reactions |
| Materials Science | Building block for functional organic materials | Acts as an electron-donating unit in the synthesis of fluorescent probes or organic semiconductor materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities by gradient HPLC separation and UV detection, relative to main peak response. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., methanol, acetone) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated in situ via reaction with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni) after acid digestion by detecting elemental ions based on mass-to-charge ratio. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after anion-exchange column separation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established visual standards. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing, indicating inorganic impurity load. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral molecules to confirm enantiomeric identity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension by analyzing angular scattering pattern of laser beam. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode and reference electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 52–56°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.