2,5-DIBROMO-6-METHYLPYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 39919-65-8 |
| Product name | 2,5-DIBROMO-6-METHYLPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,5-DIBROMO-6-METHYLPYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,5-DIBROMO-6-METHYLPYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,5-DIBROMO-6-METHYLPYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Used as a key brominated heterocyclic intermediate in cross-coupling reactions—such as Suzuki and Heck couplings—to construct C–C bonds |
| Agrochemical Intermediates | Synthesis of novel insecticides and fungicides (e.g., pyridine derivatives) | Functional groups are introduced onto the pyridine ring via nucleophilic substitution or metal-catalyzed coupling to enhance biological activity |
| Organic Synthesis | Preparation of functional material monomers and ligands (e.g., bromopyridine-based ligands for metal–organic frameworks) | The bromine atom serves as a leaving group in substitution reactions or is further converted to hydroxyl, amino, cyano, or other functional groups |
Manufacturing Quality Control of 2,5-DIBROMO-6-METHYLPYRIDINE
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Inspect the sample by eye for color, physical state (e.g., white to off-white crystalline powder), and presence of visible impurities to determine compliance with quality standards. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as mobile phase under isocratic or gradient elution. The main peak is detected by a UV detector (typically at 254 nm), and purity is calculated based on peak area (typically required to be ≥98.0%). |
| Assay | Gas Chromatography (GC) or HPLC | GC is suitable for volatile samples, using a capillary column and FID detector; however, HPLC is more commonly used. Quantification of 2,5-dibromo-6-methylpyridine is performed via external standard or internal standard method, with results expressed as weight percentage. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | In accordance with ICH Q3C guidelines, residual organic solvents (e.g., toluene, dichloromethane, methanol) are analyzed using headspace sampling coupled with FID detection to ensure levels are within acceptable safety limits. |
| Moisture Content | Karl Fischer Titration | Determines water content based on the quantitative reaction between water in the sample and Karl Fischer reagent, using either coulometric or volumetric titration. Controls product dryness (typically requires ≤0.5%). |
| Melting Point | Capillary Melting Point Method | The sample is packed into a capillary tube and heated at a specified rate in a melting point apparatus. The initial and final melting temperatures are recorded, used for identification and purity assessment (literature melting point approximately 78–82 °C). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After digestion of the sample, heavy metal elements such as lead, cadmium, mercury, and arsenic are measured by AAS or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) to ensure compliance with pharmacopoeial or regulatory limits (e.g., ≤20 ppm). |
| Related Substances (Impurities) | HPLC Gradient Elution Method | A high-sensitivity HPLC method with gradient elution is used to separate the main component from potential process-related impurities or degradation products. Individual impurity levels are calculated using area normalization or correction factor methods, with limits typically set at ≤0.5% for any single impurity and ≤1.0% for total impurities. |
Technical Specifications of 2,5-DIBROMO-6-METHYLPYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to orange to green crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72-76°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,5-DIBROMO-6-METHYLPYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,5-DIBROMO-6-METHYLPYRIDINE
Packaging of 2,5-DIBROMO-6-METHYLPYRIDINE
Industrial 2,5-DIBROMO-6-METHYLPYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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