China Factory Direct
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| CAS number | 39994-75-7 |
| Product name | Methyl L-threoninate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of amino acid-based drug intermediates | Used as a chiral building block in the preparation of antibiotics, antiviral agents, and other active pharmaceutical ingredients |
| Biochemical Research | Starting material for amino acid derivative synthesis | Applied in peptide synthesis for introducing and coupling protected amino acids |
| Fine Chemicals | Organic synthesis reagent | Participates in esterification, amidation, and other reactions to construct complex molecular frameworks |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at 205 nm. |
| Optical Rotation | [alpha]D | Measurement of plane-polarized light rotation in solution to confirm chiral integrity and enantiomeric purity. |
| Water Content | Karl Fischer titration | Electrochemical titration using iodine generation to quantify water content based on stoichiometric reaction with Karl Fischer reagent. |
| Residue on Ignition | Gravimetric analysis | Determination of non-volatile inorganic impurities by high-temperature ashing followed by weighing of residual ash. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals | ICP-OES | Multi-element detection of Pb, Cd, Hg, As, and other heavy metals after acid digestion via plasma excitation and optical emission spectroscopy. |
| Related Substances | HPLC with gradient elution | Identification and quantification of structurally related impurities (e.g., L-threonine, methyl ester hydrolysis products) using retention time and peak area comparison. |
| pH (1% aqueous solution) | Potentiometric pH measurement | Determination of hydrogen ion activity using calibrated glass electrode in a standardized aqueous solution. |
| Sulfated Ash | Gravimetric analysis | Quantification of inorganic sulfate residue after combustion with sulfuric acid treatment and subsequent weighing. |
| Loss on Drying | Thermogravimetric analysis (TGA) or oven drying | Measurement of volatile mass loss upon controlled heating under specified temperature and time conditions. |
| Specific Optical Rotation | Polarimetry | Direct measurement of specific rotation using sodium D-line light source and defined path length/concentration. |
| Microbial Limits | Membrane filtration and colony counting | Enumeration of aerobic mesophilic microorganisms and detection of specified pathogens per pharmacopeial methods. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow sticky liquid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -11.0 to -9.0 deg (c=1, H2O) |
| Melting Point | 148 to 152 °C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.