Nitroxoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4008-48-4 |
| Product name | Nitroxoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Nitroxoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Nitroxoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Nitroxoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antimicrobial agent; intermediate for antimalarial drugs | Used as a key intermediate in the synthesis of quinoline-based pharmaceuticals (e.g., chloroquine), where the active molecular scaffold is constructed via nitration, reduction, and diazotization reactions |
| Agrochemicals | Intermediate for fungicides | Applied in the synthesis of quinoline-containing agricultural fungicides, such as by alkylation with haloalkanes to produce biologically active derivatives |
| Analytical Chemistry | Chelating agent for metal ions; fluorescent probe | Forms stable, colored complexes with metal ions (e.g., Al³⁺, Mg²⁺, Zn²⁺) within pH 4–7, enabling detection via spectrophotometric or fluorometric methods |
| Materials Science | Precursor for organic luminescent materials; ligand for metal–organic frameworks (MOFs) | Acts as a bidentate chelating ligand coordinating with transition metals (e.g., Zn²⁺, Cu²⁺) to prepare fluorescent sensing materials or catalytic MOFs |
Manufacturing Quality Control of Nitroxoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine water content based on stoichiometric reaction with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue mass expressed as percentage of original sample. |
| Heavy Metals (as Pb) | AAS (Flame or Graphite Furnace) | Atomic absorption spectroscopy after acid digestion; measures absorbance of ground-state atoms at characteristic wavelength for lead. |
| Chloride Impurity | Ion Chromatography | Separation of anions on ion-exchange column with conductivity detection; quantification via external calibration curve. |
| Sulfate Impurity | Turbidimetry | Reaction with barium chloride under acidic conditions to form BaSO4 precipitate; measurement of turbidity at 420 nm. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Organic Volatile Impurities | GC-FID | Gas chromatographic separation followed by flame ionization detection; quantified against internal standard or external calibration. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measurement of hydrogen ion activity in saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of light scattering pattern from dispersed particles to calculate size distribution based on Mie theory. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Weight loss measured upon heating under controlled nitrogen atmosphere from 25 C to 105 C; reported as % mass loss. |
Technical Specifications of Nitroxoline
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 182–186 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Nitroxoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Nitroxoline
Packaging of Nitroxoline
Industrial Nitroxoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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