China Factory Direct
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| CAS number | 40126-30-5 |
| Product name | H-CIS-HYP-OME HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in peptide drug synthesis | Used in solid-phase or solution-phase peptide synthesis to incorporate the cis-4-hydroxy-L-proline moiety as a structural unit for constructing peptide therapeutics with specific biological activity (e.g., antifibrotic agents, peptide hormones). |
| Pharmaceutical Industry | Drug molecule structural modification and optimization | Employed as a chiral building block to synthesize lead compounds containing a pyrrolidine ring, enhancing metabolic stability or aqueous solubility. |
| Chemical Industry | Chiral catalysts or ligands for asymmetric synthesis | Converted via derivatization into chiral catalysts or ligands—leveraging its chiral center and hydroxyl functionality—for use in asymmetric catalytic reactions. |
| Research | Biochemical and organic synthesis studies | Served as a reference standard or model compound to investigate the effects of cis/trans isomerism on peptide chain folding, three-dimensional conformation, and biological activity. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 200-220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities (e.g., diastereomers, hydrolysis products) using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Optical Rotation | [alpha]D | Measurement of specific optical rotation using a polarimeter at 20-25 C with sodium D-line (589 nm); verifies chiral integrity and enantiomeric excess. |
| Residual Solvents | GC-FID | Quantitative determination of residual solvents (e.g., methanol, dichloromethane) by gas chromatography with flame ionization detection, using internal standard calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, As, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Direct measurement of hydrogen ion activity in a standardized aqueous solution using calibrated glass electrode pH meter. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after high-temperature (700-800 C) ashing of sample; indicates non-volatile inorganic impurities. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic bacteria, yeasts, and molds via filtration, membrane transfer to selective media, and colony counting after incubation. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering patterns to calculate volume-based particle size distribution (D10, D50, D90). |
| Test Item | Specification |
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| Appearance | Off-white crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Optical Rotation | -11.0 to -9.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.