China Factory Direct
|
|
| CAS number | 402-49-3 |
| Product name | 4-(TRIFLUOROMETHYL)BENZYL BROMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing antifungal agents (e.g., fluconazole analogues) | Bromination: prepared from 4-(trifluoromethyl)benzyl alcohol using hydrobromic acid or phosphorus tribromide |
| Pesticides | Structural building block for trifluoromethylphenyl-based insecticides and fungicides | Nucleophilic substitution: reacts with amines or thiols to form C–N or C–S bonds |
| Materials Science | Precursor for electron-transport layer materials in organic light-emitting diodes (OLEDs) | Suzuki or Heck coupling: serves as an aryl halide in palladium-catalyzed cross-coupling to introduce the trifluoromethylphenyl moiety |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, state, and presence of impurities under natural light or standard illumination; it should typically be a colorless to pale yellow transparent liquid. |
| Purity | Gas Chromatography (GC) | Analysis is performed using a capillary column with a FID detector. The main component content is calculated by comparing retention times with a reference standard and applying peak area normalization. |
| Water Content | Karl Fischer Titration | Quantitative determination of trace water content based on the stoichiometric reaction between iodine and sulfur dioxide in a pyridine/methanol system, measured via potentiometric titration. |
| Boiling Point/Boiling Range | Distillation (Atmospheric or Reduced Pressure) | Measure the initial and final boiling points using a standard distillation apparatus to verify whether the boiling range complies with specified requirements (e.g., literature value: approximately 220–225 °C at 760 mmHg). |
| Refractive Index | Abbe Refractometer | Measure the refractive index of the sample at a specified temperature (typically 20 °C or 25 °C) as an auxiliary indicator for identification and purity assessment. |
| Density | Densitometry or Pycnometer Method | Measure the ratio of mass to volume at a standard temperature to verify consistency of physical properties. |
| Residual Solvents | Gas Chromatography (Headspace or Direct Injection) | Use GC-FID or GC-MS to detect possible residual organic solvents (e.g., dichloromethane, toluene), with concentration limits controlled according to ICH Q3C guidelines. |
| Halogen Content (Bromine) | Oxygen Bomb Combustion-Ion Chromatography or Potentiometric Titration | After oxygen bomb combustion, bromide ions in the absorption solution are quantified via ion chromatography, or titrated potentiometrically with standard silver nitrate solution to verify whether bromine content conforms to theoretical values. |
| Related Substances (Impurities) | Gas Chromatography-Mass Spectrometry (GC-MS) or High-Performance Liquid Chromatography (HPLC) | Employ high-resolution separation techniques to identify and quantify potential by-products or degradation products (e.g., 4-trifluoromethylbenzaldehyde, 4-trifluoromethylbenzyl alcohol), ensuring total impurity levels remain within acceptable limits. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow semi-solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 35–39°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.