4-(Trifluoromethyl)anisole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 402-52-8 |
| Product name | 4-(Trifluoromethyl)anisole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(Trifluoromethyl)anisole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(Trifluoromethyl)anisole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(Trifluoromethyl)anisole
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of anti-inflammatory, antitumor, or central nervous system-active compounds | Introduces the trifluoromethoxybenzene structural motif via electrophilic substitution, metal-catalyzed coupling, or reduction reactions |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of bioactive herbicides or insecticides | Prepares target molecules via aromatic ring functionalization (e.g., halogenation, nitration) or heterocycle construction reactions |
| Liquid Crystal Materials | Used as a liquid crystal monomer or intermediate in the synthesis of trifluoromethyl-containing liquid crystal compounds | Constructs the liquid crystal core structure via Williamson ether synthesis, Suzuki coupling, and related methods |
| Organic Synthesis | Used as a trifluoromethylated aromatic ether building block for constructing complex molecular frameworks | Serves as a starting material in palladium-catalyzed cross-coupling, nucleophilic substitution, or oxidative addition reactions |
Manufacturing Quality Control of 4-(Trifluoromethyl)anisole
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water in the sample. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after high-temperature ashing at 700–800 °C. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element quantitative detection via measurement of element-specific atomic emission lines after acid digestion. |
| Chlorinated Impurities (e.g., o-chloro-p-trifluoromethyl anisole) | Gas Chromatography–Mass Spectrometry (GC-MS) | Identification and quantification of structurally related chlorinated impurities using retention time and characteristic mass fragments. |
| Acidity (as HCl) | Acid-Base Potentiometric Titration | Neutralization of acidic impurities with standardized sodium hydroxide solution; endpoint detected by pH electrode. |
| Color (APHA) | Visual Comparison or Spectrophotometric Measurement (430 nm) | Quantification of yellowness intensity relative to platinum-cobalt standard solutions. |
| Refractive Index | Refractometry (at 20 °C) | Measurement of light bending angle in the liquid sample, correlated to purity and molecular composition. |
| Density | Oscillating U-tube Densitometry | Determination of mass per unit volume based on resonant frequency shift of a vibrating sample-filled tube. |
| Non-Volatile Residue | Evaporation–Gravimetry | Weighing residual material after gentle evaporation of a defined sample volume under controlled temperature and airflow. |
| Residual Solvents (e.g., methanol, toluene) | Headspace Gas Chromatography (HS-GC) with FID | Quantitative analysis of volatile organic solvents via equilibrium partitioning into headspace followed by GC separation. |
| Optical Rotation | Polarimetry (at 20 °C, sodium D-line) | Measurement of rotation angle of plane-polarized light, confirming absence of chiral contamination (though compound is achiral, detects chiral impurities). |
Technical Specifications of 4-(Trifluoromethyl)anisole
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.475–1.485 |
| Relative Density (20°C/25°C) | 1.180–1.195 g/cm³ |
| Odor | Characteristic aromatic odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(Trifluoromethyl)anisole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(Trifluoromethyl)anisole
Packaging of 4-(Trifluoromethyl)anisole
Industrial 4-(Trifluoromethyl)anisole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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