China Factory Direct
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| CAS number | 40296-46-6 |
| Product name | Ethyl 4,6-dichloronicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibacterial and antiviral drug intermediates | Used in organic synthesis and esterification reactions |
| Agrochemicals | Production of active ingredient precursors for insecticides and herbicides | Applied in chlorination and catalytic hydrogenation reactions |
| Materials Science | Preparation of modified monomers for polymer or functional chemical synthesis | Employed in polymerization and conjugate addition reactions |
| Research & Development | Organic synthesis intermediate for new compound screening | Used in laboratory-scale trials and structural optimization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 220-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., mono-chloro analogs, hydrolysis products) by gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Determines trace levels of solvents (e.g., ethanol, toluene, THF) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion by measuring atomic emission intensities at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Determines total chloride ions using silver nitrate titrant and silver/silver chloride indicator electrode based on precipitation endpoint detection. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid groups (if hydrolyzed) via titration with standardized NaOH using phenolphthalein or potentiometric endpoint. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against standard white background under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per pharmacopeial guidelines. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration (600-800 C) and weighing of residual non-volatile matter. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by determining rotation angle of plane-polarized light in solution using sodium D-line (589 nm). |
| Bulk Density | Tap Density Measurement | Determines mass per unit volume of freely settled and tapped powder using standardized cylinder and tapping device per USP <616>. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC) |
| Total Impurities | <=2.0% (GC) |
| Single Impurity | <=0.5% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 68–72°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.