3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 403-01-0 |
| Product name | 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antibacterial agents, used in the synthesis of fluoroquinolone antibiotics (e.g., gatifloxacin, sparfloxacin) | Undergoes substitution reaction with piperazine derivatives to construct the quinolone core structure |
| Agrochemicals | Intermediate for herbicides and fungicides | Participates in heterocyclic coupling reactions to prepare fluorinated benzothiazole active ingredients |
| Materials | Precursor for liquid crystal monomers and functional materials for organic light-emitting diodes (OLEDs) | Fluorination is introduced via ester hydrolysis, diazotization–fluoroborate thermal decomposition, or palladium-catalyzed fluorination, followed by coupling polymerization |
Manufacturing Quality Control of 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using gradient HPLC with diode-array detection; identification and quantification based on retention time and spectral match. |
| Residual Solvents | GC-FID | Volatile organic solvents quantified by gas chromatography with flame ionization detection using headspace sampling and internal standard calibration. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine generated electrochemically or added reagent; water reacts stoichiometrically with iodine in pyridine/methanol medium. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion; detection based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation of anions on ion-exchange column with suppressed conductivity detection; chloride quantified using external calibration. |
| Sulfated Ash | Gravimetric Analysis | Sample incinerated at 600-700 C, residue treated with sulfuric acid and ignited to constant weight; ash content calculated as percentage of original sample. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, measured using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution; reported as [alpha]D at specified concentration and temperature. |
| Residual Catalyst (Pd) | ICP-MS | Ultra-trace palladium quantified after microwave-assisted acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of substance against defined standards under controlled lighting conditions. |
| pH of Aqueous Solution | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode system per EP 2.2.3. |
Technical Specifications of 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
Safety Information of 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER
Industrial 3-FLUORO-4-HYDROXY-BENZOIC ACID METHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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