China Factory Direct
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| CAS number | 403-17-8 |
| Product name | 4-Chloro-3-fluorobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Serves as an aryl carboxylic acid source to introduce functional groups during the synthesis of fluoroquinolone antibacterial agents or other fluorinated drug molecules. |
| Agrochemicals | Agrochemical Intermediate | Used in the synthesis of fluorinated herbicides or fungicides, leveraging the electron-withdrawing effect and metabolic stability conferred by fluorine atoms to enhance biological activity. |
| Organic Synthesis | Precursor for Functional Materials | Converted via further derivatization (e.g., reduction, esterification, coupling) into fluorinated benzoate or benzyl alcohol derivatives for high-performance materials or liquid crystal monomer synthesis. |
| Research Reagents | Synthetic Building Block | Undergoes Suzuki coupling, amidation, or nucleophilic substitution reactions—exploiting dual reactivity of the carboxyl and halogen (chlorine or fluorine) groups—to construct complex organic molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by reverse-phase HPLC with UV detection at 230-254 nm using external standard calibration. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against reference standards or area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water via electrochemical reaction stoichiometry. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element determination after acid digestion, measuring emission intensities at characteristic wavelengths for metals. |
| Chloride Impurity | Ion Chromatography | Separation of anions on anion-exchange column with suppressed conductivity detection for quantitative chloride analysis. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range where solid transforms to liquid. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying sample at specified temperature (e.g., 105 C) under vacuum or air until constant mass. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Residue on Ignition | Gravimetric Ashing | Mass of non-volatile inorganic residue remaining after high-temperature (700-800 C) ignition of sample in platinum crucible. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to calculate volume-based particle size distribution in dispersed sample. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 148–152°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.