China Factory Direct
|
|
| CAS number | 404-01-3 |
| Product name | 3',5'-DIFLUOROACETANILIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate for synthesizing fluoroquinolone antibiotics (e.g., ciprofloxacin derivatives) | Used to prepare active pharmaceutical ingredients via acylation, fluorination, and other steps using trifluoroacetic anhydride or fluorinating agents |
| Agrochemicals | Herbicide and fungicide intermediate for constructing fluorinated aniline-based agrochemicals | Serves as a key aromatic amine building block in diazotization-coupling and nucleophilic substitution reactions to synthesize target agrochemicals |
| Materials | High-performance polymer monomer for producing heat- and chemical-resistant fluorinated polyamides/polyimides | Undergoes condensation polymerization with diacids or acid anhydrides to form fluorinated aromatic polyamide backbones, enhancing thermal stability |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~230 nm. |
| Related Substances (Impurities) | HPLC-UV or GC-FID | Separation and quantification of structurally related impurities (e.g., 3,5-difluoroaniline, acetic anhydride residues) using gradient HPLC or capillary GC with flame ionization detection. |
| Residual Solvents (e.g., Acetone, Ethyl Acetate) | GC-FID or GC-MS | Headspace GC analysis with FID or MS detection to quantify volatile organic solvents per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS or ICP-OES | Digestion followed by multi-element quantification using inductively coupled plasma mass spectrometry or optical emission spectroscopy for trace metal contaminants. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate (e.g., 1–2 °C/min). |
| Chloride Impurity | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification via suppressed conductivity detection (IC) or argentometric titration with silver nitrate endpoint detection. |
| Appearance and Color | Visual Inspection & APHA Color Scale | Subjective assessment of physical state (crystalline powder) and color intensity compared to platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of non-volatile inorganic residue after high-temperature ashing (700–800 °C) and weighing. |
| pH of Aqueous Suspension | pH Meter Measurement | pH measurement of a saturated aqueous suspension (e.g., 1% w/v) using calibrated pH electrode to assess acidic/basic degradation products. |
| Bulk Density | ASTM D1895 Method A (Tapped Density) | Measurement of mass per unit volume after mechanical tapping to assess powder flow and handling characteristics. |
| Particle Size Distribution | Laser Diffraction (PSD) | Analysis of particle size distribution in dispersed phase using Mie scattering theory and optical diffraction patterns. |
| Specific Optical Rotation | [α]D | Measurement of rotation angle of plane-polarized light at 589 nm to confirm chiral purity (though compound is achiral; used to detect chiral contaminants or enantiomeric impurities if present). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 102.0 - 106.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.