China Factory Direct
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| CAS number | 4042-36-8 |
| Product name | D-Pyroglutamic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediates for preparing optically active drug molecules | Used as chiral auxiliaries or building blocks in asymmetric synthesis |
| Cosmetics | Skin moisturizer and anti-aging ingredient | Incorporated into skincare formulations to enhance skin barrier function, leveraging its properties as a natural amino acid derivative |
| Food | Flavor enhancer (research stage) | Applied to modulate flavor profiles in specific food systems; not yet deployed at scale |
| Agriculture | Plant growth regulator (experimental) | Applied as a signaling molecule analog to influence plant physiological processes; currently limited to laboratory research |
| Biotechnology | Enzyme inhibitor or ligand | Used to study enzyme–substrate interactions or as a receptor-binding probe |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Acid-Base Titration | Quantifies D-pyroglutamic acid content by titration with standardized NaOH using phenolphthalein indicator. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric reaction of water with iodine, sulfur dioxide, and base in methanol. |
| Specific Optical Rotation | Polarimetry | Measures the angle of rotation of plane-polarized light caused by chiral D-pyroglutamic acid in solution. |
| Heavy Metals | ICP-OES | Quantifies trace metal impurities (e.g., Pb, Cd, As) via atomic emission from plasma-excited sample aerosol. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Barium Sulfate Turbidimetry | Forms insoluble BaSO4 precipitate; quantifies sulfate via turbidity measurement at 420 nm. |
| Related Substances | HPLC-UV | Separates and detects structurally related impurities (e.g., L-isomer, pyroglutamic acid derivatives) using reversed-phase column and UV detection at 210 nm. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in a 1% w/v aqueous solution using calibrated pH electrode. |
| Loss on Drying | Thermogravimetric Analysis | Measures mass loss upon heating at 105 C for 2 hours, reflecting volatile content including residual solvents and moisture. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar media, and colony enumeration after incubation. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution by measuring angular variation in intensity of laser light scattered by dispersed particles. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 136.0 - 140.0 °C |
| Optical Rotation | +8.0 to +12.0 ° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.