China Factory Direct
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| CAS number | 4043-87-2 |
| Product name | DL-Pipecolinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediates for antidepressants, analgesics, and neuroactive drugs | Used as chiral auxiliaries or building blocks in multistep organic synthesis, including condensation with acyl chlorides and reductive amination |
| Pharmaceuticals | Non-natural α-amino acid derivatives for structural modification of peptide-based therapeutics | Incorporated into peptide chains via solid-phase peptide synthesis (SPPS) or solution-phase coupling to enhance metabolic stability and receptor selectivity |
| Agrochemicals | Structural motif for novel insecticides and plant growth regulators | Modified via N-alkylation, epoxidation, or coupling with heterocycles to optimize target binding affinity and environmental degradability |
| Materials Science | Functional monomer for pH-responsive hydrogels | Copolymerized with acrylic monomers; the tertiary amine group in the piperidine ring enables protonation/deprotonation-driven swelling behavior |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration with NaOH | Quantifies 2-piperidinecarboxylic acid by neutralizing with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration | Measures water content based on the stoichiometric reaction of iodine with water in a methanol-based reagent under controlled conditions. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic impurities by ignition at 700-800 C and weighing the residual ash. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion by measuring atomic absorption at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using an anion-exchange column and conductivity detection. |
| Sulfate Impurity | Ion Chromatography (IC) | Separates and quantifies sulfate ions using an anion-exchange column and conductivity detection. |
| Related Substances | High Performance Liquid Chromatography (HPLC) | Separates and quantifies structurally related impurities using reversed-phase C18 column and UV detection at 210 nm. |
| Optical Rotation | Polarimetry | Measures specific optical rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines melting range by observing phase transition under controlled heating; indicates purity and identity. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Measures mass loss upon heating to 105 C for 2 hours to determine volatile content including residual solvents. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a 1% w/v aqueous solution using calibrated pH electrode. |
| Residual Solvents | Gas Chromatography (GC) with FID | Quantifies common organic solvents (e.g., methanol, acetone, ethyl acetate) using headspace GC-FID and external calibration. |
| Test Item | Specification |
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| Appearance | Very slightly beige solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 134-138°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +17.0 to +19.0° (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.