China Factory Direct
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| CAS number | 4045-22-1 |
| Product name | 1-ACETYLPIPERIDIN-4-OL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of opioid analgesics (e.g., fentanyl and its derivatives) | Acetylation introduces the acetyl group; participates in multi-step organic synthesis to construct the piperidine ring structure |
| Agrochemicals | Intermediate in the synthesis of certain insecticides or herbicides | Serves as a nitrogen-containing building block in heterocyclic compound synthesis; active ingredients are prepared via subsequent functional group transformations |
| Chemical Research | Model compound or building block for medicinal chemistry and organic synthetic methodology studies | Structural modification and derivatization via nucleophilic substitution, reduction, coupling, and other reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies 1-acetyl-4-piperidine by retention time and peak area against a calibrated standard. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by weight measurement. |
| Acid Value | Acid-Base Titration with NaOH | Neutralizes free acidic impurities using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against specified standards under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral molecules in solution at specified concentration and path length. |
| Heavy Metals | ICP-OES | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg, As) after acid digestion using plasma emission spectroscopy. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detects and quantifies volatile organic solvents (e.g., acetone, methanol) using equilibrium vapor phase analysis. |
| Melting Point | Capillary Melting Point Determination | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions based on anion exchange and conductivity detection. |
| Related Substances | HPLC with UV Detection | Identifies and quantifies structurally related impurities using reverse-phase chromatography and UV absorbance. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode and pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 102-106°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.