China Factory Direct
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| CAS number | 4046-02-0 |
| Product name | Ethyl 4-hydroxy-3-methoxycinnamate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent GradeIndustrial GradeSpecialty GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Antioxidant | Used as a pharmaceutical ingredient in the preparation of antioxidant formulations |
| Pharmaceuticals | Anti-inflammatory agent | Applied in the synthesis of anti-inflammatory compounds |
| Pharmaceuticals | Antiplatelet agent | Used in cardiovascular disease treatment research |
| Cosmetics | Skin care ingredient | Incorporated into skin care products to provide antioxidant and anti-aging effects |
| Food | Food additive | Applied as an antioxidant to extend shelf life |
| Fine chemicals | Synthetic intermediate | Used as an organic synthetic intermediate for the preparation of other derivatives |
| Agriculture | Plant growth regulator research | Applied in plant physiology studies to modulate plant growth responses |
| Research | Biochemical research reagent | Used in biochemical research for enzyme inhibition or signal pathway modulation experiments |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~320 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD or HPLC-MS | Separation and identification of impurities (e.g., unreacted阿魏酸, ethanol, ethyl acetate, degradation products) via retention time matching and spectral/fragmentation analysis. |
| Residual Solvents (Ethanol, Ethyl Acetate, Methanol) | GC-FID | Headspace GC with flame ionization detection, quantifying volatile solvents against internal/external calibration standards per ICH Q3C. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification after acid digestion, offering sub-ppt detection limits and compliance with ICH Q3D. |
| Acid Value | Acid-Base Titration (NaOH in ethanol) | Neutralization of free carboxylic acid groups (e.g., from hydrolyzed阿魏酸乙酯) with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | High-temperature incineration followed by sulfuric acid treatment and weighing of inorganic residue to assess inorganic impurities. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Scale | Subjective assessment of clarity and color intensity against platinum-cobalt standards per USP <1091>. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement detecting solid-to-liquid phase change; used for identity and purity verification (sharp range expected). |
| Specific Optical Rotation | [α]D Measurement (Polarimetry) | Determination of chiral purity and identity by measuring rotation of plane-polarized light at 589 nm, referenced to defined concentration and path length. |
| Residual Catalyst (e.g., H₂SO₄, p-TSA) | Ion Chromatography (IC) or pH Titration | Quantification of acidic catalyst residues via suppressed conductivity detection (IC) or neutralization titration to endpoint. |
| Peroxide Value | Iodometric Titration | Oxidation of iodide to iodine by organic peroxides, followed by titration with standardized thiosulfate solution. |
| Microbial Limits | Membrane Filtration / Plate Count | Enumeration of aerobic microorganisms and absence testing for specified pathogens per Ph. Eur. 5.1.4 and USP <61>/<62>. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72–76°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.