China Factory Direct
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| CAS number | 405-50-5 |
| Product name | 4-Fluorophenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), such as flurbiprofen and ibuprofen | Participates in drug molecule construction via acylation, amination, and cyclization steps |
| Agrochemicals | Structural building block for fluorinated insecticides and fungicides | Introduces fluorinated side chains into active molecules to enhance lipophilicity and biological activity |
| Materials | Used to prepare fluorinated liquid crystal monomers and functional materials for organic light-emitting diodes (OLEDs) | Introduces rigid fluorinated groups into target molecules via esterification, coupling, or polymerization reactions to modulate optoelectronic properties |
| Detection Item | Common Testing Method | Method Overview |
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| Appearance | Visual Inspection | Observe the sample's color, physical state, and visible impurities under natural light or standard illumination. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, detect with UV detector (typically around 254 nm), and quantify the main component using external standard or internal standard method. |
| Purity Analysis | Gas Chromatography (GC) or HPLC | GC is suitable for samples with good volatility; HPLC is more commonly used, effectively separating the main peak from impurity peaks, calculating total purity via normalization or area percentage method. |
| Related Substances (Impurities) | HPLC Method | Use gradient elution program to detect potential synthetic intermediates, by-products, or degradation products; calculate impurity content based on peak area. |
| Melting Point | Melting Point Instrument Method | Determine initial and final melting temperatures using capillary tube method or automated melting point instrument, to assess purity and consistency. |
| Moisture Content | Karl Fischer Titration (KF) | Accurately determine moisture content using KF titrator; available in volumetric and coulometric methods, suitable for trace moisture detection. |
| Residual Solvents | Gas Chromatography (GC) | Follow ICH guidelines to detect organic solvents (e.g., methanol, ethanol, ethyl acetate) potentially left over from production processes; use headspace injection mode. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, detect levels of heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial or relevant quality standards. |
| pH Value (Solution) | pH Meter Measurement | Determine the acidity or alkalinity of a solution (e.g., 1% w/v aqueous solution of 4-fluorophenylacetic acid) using a pH meter, reflecting its ionization characteristics. |
| Infrared Spectroscopy Identification (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain infrared spectrum via pellet method (KBr), compare with reference spectrum to confirm functional groups and compound identity. |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹⁹F-NMR | Dissolve sample in deuterated solvent (e.g., DMSO-d6), analyze proton and fluorine spectra to verify molecular structure, used for raw material confirmation or impurity structural elucidation. |
| Test Item | Specification |
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| Appearance | White Solid |
| ldentification(NMR) | Conforms to structure |
| Purity | ≥95.0% |
| Total of impurities | Maximum 1.00 percent |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.