5-BROMO-3-CYANO-2-HYDROXYPYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 405224-22-8 |
| Product name | 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antiviral, antitumor, and central nervous system agents | Functionalized via bromination and cyanation on the 2(1H)-pyridone scaffold, followed by purification for subsequent coupling or cyclization reactions |
| Agrochemicals | Employed as a structural building block for novel insecticides or fungicides | Serves as a heterocyclic core, coupled with nitrogen- or sulfur-containing groups in multistep syntheses to construct bioactive molecules |
| Chemical Research | Utilized as an organic synthetic building block for developing novel nitrogen-containing heterocyclic compounds | Modified with diverse substituents via metal-catalyzed cross-coupling (e.g., Suzuki, Sonogashira) or nucleophilic substitution reactions |
Manufacturing Quality Control of 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element quantification after acid digestion by measuring metal isotope signals with high sensitivity and low detection limits. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection for quantitative chloride determination. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid-to-liquid phase transition occurs, using calibrated capillary apparatus. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volume-based particle size distribution in dry or wet dispersion. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a defined suspension (e.g., 1% w/v in water). |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms following filtration, membrane transfer to agar media, and colony counting after incubation. |
Technical Specifications of 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (by NMR) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178–182 °C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
Safety Information of 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE
Industrial 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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