4,4'-Dimethoxytrityl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 40615-36-9 |
| Product name | 4,4'-Dimethoxytrityl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,4'-Dimethoxytrityl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,4'-Dimethoxytrityl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,4'-Dimethoxytrityl chloride
| Industry | Application | Process |
|---|---|---|
| Chemical Synthesis | Used as a hydroxyl protecting reagent, particularly in oligonucleotide and carbohydrate synthesis | Reacts with alcohols or phenols under basic conditions to form stable trityl ethers; deprotection is achieved under acidic conditions |
| Biopharmaceuticals | Used in the synthesis of modified nucleosides, oligonucleotides, and nucleic acid analogues | Selectively protects the 5′-hydroxyl group in solid-phase or solution-phase synthesis to improve synthetic efficiency and product purity |
| Analytical Chemistry | Used as a derivatization reagent for detection and separation of hydroxyl-containing compounds | Following reaction with the target molecule, analysis is performed by HPLC or mass spectrometry to enhance detection sensitivity and selectivity |
| Materials Science | Serves as an intermediate for synthesizing functionalized polymers or surface-modified materials | Enables precise molecular design by controlling functional group reactivity through protection/deprotection strategies |
Manufacturing Quality Control of 4,4'-Dimethoxytrityl chloride
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity | High-Performance Liquid Chromatography (HPLC) | Reverse-phase C18 column is used, with methanol-water or acetonitrile-water as the mobile phase, and UV detection (typically at 254 nm or 280 nm wavelength). The main peak area is measured, and the purity of 4,4'-dimethoxytriphenylmethyl chloride is calculated using area normalization or external standard method. |
| Content | HPLC External Standard Method or Non-aqueous Titration | HPLC External Standard Method: A calibration curve is constructed using a reference standard of known concentration to determine the analyte content in the sample; Non-aqueous Titration: Conducted in anhydrous ethanol or glacial acetic acid medium using perchloric acid as titrant, with potentiometric or indicator endpoint detection. This method is suitable for quantitative analysis of halogen-containing compounds. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection is employed, with DB-624 or similar polar capillary columns for separation and FID detection for quantifying common organic solvents (e.g., dichloromethane, toluene, ethanol) residual levels, in compliance with ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Utilizes Karl Fischer reagent to react quantitatively with water in the sample, measured via coulometric or volumetric methods. This technique is suitable for moisture-sensitive organic compounds. |
| Melting Point | Capillary Melting Point Determination | Dried sample is packed into a melting point capillary tube and heated at a controlled rate. The temperature range from initial melting to complete melting is observed, used to assess substance purity and crystalline form consistency. |
| Appearance/Color | Visual Color Comparison | Sample appearance and color are evaluated under specified lighting conditions by comparing with standard reference solutions or a white background with black text. Typically, the material should be a white to off-white crystalline powder. |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Gradient elution program (e.g., acetonitrile-water system) is applied to extend run time, enabling separation of potential process impurities and degradation products. Impurities are identified by comparison with reference standards or retention time, and reported as percentage area. |
Technical Specifications of 4,4'-Dimethoxytrityl chloride
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,4'-Dimethoxytrityl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,4'-Dimethoxytrityl chloride
Packaging of 4,4'-Dimethoxytrityl chloride
Industrial 4,4'-Dimethoxytrityl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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