5'-O-Dimethoxytrityl-deoxythymidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 40615-39-2 |
| Product name | 5'-O-Dimethoxytrityl-deoxythymidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5'-O-Dimethoxytrityl-deoxythymidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5'-O-Dimethoxytrityl-deoxythymidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5'-O-Dimethoxytrityl-deoxythymidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthetic intermediate for nucleoside antiviral drugs | Used as a key chiral building block to construct thymidine analog structures in anti-HIV or anti-HBV drug molecules, with active functional groups introduced via glycosylation, phosphorylation, and related steps |
| Biochemical research | Modified monomer for DNA/RNA probe and oligonucleotide synthesis | Applied as a protected thymidine phosphoramidite monomer in solid-phase synthesis; after deprotection, it participates in sequence assembly to enhance coupling efficiency and product purity |
Manufacturing Quality Control of 5'-O-Dimethoxytrityl-deoxythymidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies thymidine content by separation on a reversed-phase column and UV detection at 267 nm. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based redox reaction. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg) by inductively coupled plasma mass spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residue. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral integrity and identity. |
| pH of Solution | Potentiometric pH Measurement | Determines acidity/basicity of aqueous solution using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or dispersed particle size by measuring angular scattering pattern of laser beam. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to agar, and colony enumeration. |
| Endotoxins | LAL Assay | Quantifies bacterial endotoxins using Limulus amebocyte lysate coagulation cascade. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
Technical Specifications of 5'-O-Dimethoxytrityl-deoxythymidine
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | +5.0 to +9.0 (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5'-O-Dimethoxytrityl-deoxythymidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5'-O-Dimethoxytrityl-deoxythymidine
Safety Information of 5'-O-Dimethoxytrityl-deoxythymidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5'-O-Dimethoxytrityl-deoxythymidine
Industrial 5'-O-Dimethoxytrityl-deoxythymidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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