2,6-DICHLORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 408492-27-3 |
| Product name | 2,6-DICHLORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 408492-27-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 408492-27-3 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 408492-27-3
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used as a key boronate reagent in Suzuki coupling reactions to construct aromatic ring systems |
| Agrochemicals | Synthesis intermediates for insecticides and herbicides | Applied in transition metal-catalyzed cross-coupling reactions to introduce pyridyl groups |
| Organic Synthesis | Construction of functionalized pyridine derivatives | Preparation of polysubstituted pyridine compounds via palladium-catalyzed coupling reactions |
| Materials Science | Precursor for organic semiconductor materials | Employed to synthesize nitrogen-containing aromatic conjugated systems to enhance electronic transport properties of materials |
Manufacturing Quality Control of 408492-27-3
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/water as the mobile phase, and UV detection (typically at 254 nm) to determine the percentage area of the main peak, assessing sample purity. |
| Content (Main Component Quantification) | HPLC External Standard Method or Internal Standard Method | Quantifies the target compound by comparing peak areas with those of a reference standard of known concentration, commonly used for quantitative analysis of active pharmaceutical ingredients or intermediates. |
| Related Substances (Impurities) | HPLC or UPLC | Separates and identifies potential impurities (e.g., unreacted starting materials, by-products, degradation products) under purity testing conditions; impurity levels are reported using area normalization or correction factor methods. |
| Water Content | Karl Fischer Titration | Utilizes the quantitative reaction between iodine and sulfur dioxide in a pyridine/methanol system with water, enabling accurate measurement of trace moisture—critical for the stability of borate ester compounds. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace or direct injection with FID detection; follows ICH Q3C guidelines to detect organic solvents (e.g., toluene, dichloromethane, ethanol) remaining from synthesis processes. |
| Melting Point | Melting Point Analyzer | Determines the melting temperature range using capillary tube method or digital melting point instrument, serving as a physical property identification tool and an auxiliary indicator of purity. |
| Structure Elucidation | Proton Nuclear Magnetic Resonance (¹H NMR) and Carbon-13 Nuclear Magnetic Resonance (¹³C NMR) | Confirms molecular structure through characteristic chemical shifts (e.g., neopentyl ester methyl signal ~1.3 ppm, aromatic protons ~7–8 ppm). |
| Fourier Transform Infrared Spectroscopy (FT-IR) | Identifies characteristic absorption peaks of functional groups such as B–O, C–Cl, and C=N, supporting structural confirmation. | |
| Mass Spectrometry (MS or HRMS) | Determines molecular ion peaks ([M+H]⁺ or [M+Na]⁺), confirming molecular weight and elemental composition. | |
| Inorganic Elemental Impurities (e.g., Pd, Cl) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detects residual catalysts (e.g., palladium) or halogen content, ensuring compliance with ICH Q3D guidelines for elemental impurity control. |
| Polymorphism (if applicable) | X-Ray Powder Diffraction (XRPD) | If polymorphic forms exist, XRPD patterns are used to confirm consistency of crystal form, which affects solubility and stability. |
Technical Specifications of 408492-27-3
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 408492-27-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
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Industrial 408492-27-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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