L-Norvaline ethyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 40918-51-2 |
| Product name | L-Norvaline ethyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for L-Norvaline ethyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk L-Norvaline ethyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of L-Norvaline ethyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of antibiotics, antiviral agents, and peptide-based drugs | Applied as a protected form of L-valine in solid-phase or solution-phase peptide synthesis for coupling reactions |
| Biochemical Research | Used in enzymology studies and amino acid metabolic pathway analysis | Applied as a substrate or reference standard in chromatographic analysis (e.g., HPLC) and mass spectrometry |
| Pharmaceutical Raw Materials | Used to synthesize active pharmaceutical ingredients (APIs) containing a valine structural moiety | Applied in organic synthesis steps—including esterification, deprotection, and coupling—to construct the target molecule |
Manufacturing Quality Control of L-Norvaline ethyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Chiral Purity | Chiral HPLC | Separation and quantification of enantiomers using a chiral stationary phase; L-enantiomer content determined by peak area ratio. |
| Loss on Drying | Gravimetric analysis (105 C, 2 h) | Mass loss measured after drying under standardized temperature and time to determine volatile content including residual solvents and water. |
| Residual Solvents | Gas Chromatography (GC-FID) | Identification and quantification of common organic solvents (e.g., ethanol, ethyl acetate) using flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element detection of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensity. |
| Chloride Content | Potentiometric titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| pH (1% aqueous solution) | pH meter measurement | Measurement of hydrogen ion activity in a standardized aqueous solution using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Determination of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and path length. |
| Related Substances | HPLC with gradient UV detection | Detection and quantification of structurally related impurities (e.g., L-norvaline, diethyl ester, hydrolysis products) using optimized gradient elution. |
| Water Content | Karl Fischer titration | Volumetric or coulometric determination of water based on stoichiometric reaction between iodine, sulfur dioxide, and water in pyridine/methanol medium. |
| Appearance | Visual inspection | Assessment of physical state, color, and clarity against defined standards under controlled lighting conditions. |
| Microbial Limits | Membrane filtration and plate count | Enumeration of aerobic microorganisms and absence testing for specified pathogens following pharmacopeial culture-based methods. |
Technical Specifications of L-Norvaline ethyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146 °C |
| Optical Rotation | +8.0 to +10.0 deg (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of L-Norvaline ethyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of L-Norvaline ethyl ester hydrochloride
Safety Information of L-Norvaline ethyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of L-Norvaline ethyl ester hydrochloride
Industrial L-Norvaline ethyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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