China Factory Direct
|
|
| CAS number | 41162-19-0 |
| Product name | Dimethyl (2-oxo-4-phenylbutyl)phosphonate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antihypertensive agents (e.g., amlodipine besylate analogues) | Undergoes nucleophilic substitution with amines under basic conditions to construct the dihydropyridine ring side chain |
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with UV detection (e.g., 210–230 nm), quantifying the main component via external standard method or area normalization. Suitable for samples with high purity and good stability. |
| Related Substances (Impurities) | HPLC - Gradient Elution Method | Optimizes the mobile phase gradient program to separate the main peak from potential process impurities and degradation products; uses DAD detector for peak purity analysis to ensure impurity levels comply with pharmacopoeial or company specifications. |
| Moisture Content | Karl Fischer Titration | Measures trace moisture using either titration (capacity) or coulometric method, avoiding interference from moisture that may affect phosphate ester bond stability and subsequent reactivity. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection with FID detection; quantitatively controls organic solvents (e.g., ethyl acetate, methanol, dichloromethane) potentially remaining from synthesis according to ICH Q3C guidelines. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Follows general chapters in the Chinese Pharmacopoeia or USP <232>/<233> methods to detect elemental impurities such as lead, cadmium, arsenic, mercury, and copper, ensuring compliance with safety limits. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Utilizes ¹H NMR, ³¹P NMR, and ¹³C NMR to confirm molecular framework, substitution positions, and functional group integrity—core technique for structural identification. |
| Infrared Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Compares IR spectra of sample and reference standard to verify characteristic functional group absorptions (e.g., C=O, P=O, aromatic C-H), used for rapid authentication and authenticity verification. |
| Melting Point | Digital Melting Point Apparatus | Determines melting temperature range as a physical constant for auxiliary identification and purity assessment (applicable only if solid). |
| pH (in Solution State) | pH Meter Measurement | Sample is prepared as an aqueous solution or buffer at specified concentration, and pH is measured to monitor acid-base stability and potential hydrolysis. |
| Specific Rotation (if Chiral) | Polarimeter Measurement | If the molecule contains chiral centers, specific rotation must be controlled to ensure optical purity (not applicable for this compound due to absence of chiral centers). |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.