China Factory Direct
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| CAS number | 41251-37-0 |
| Product name | METHYL-D3-MAGNESIUM IODIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used to synthesize CD3 groups in deuterated drug molecules, enhancing metabolic stability and pharmacokinetic properties | Employed as a deuterated Grignard reagent in nucleophilic addition reactions—for example, with carbonyl compounds (aldehydes, ketones, esters) to introduce the –CD3 group |
| Organic Synthesis | Used as a deuterium labeling reagent to construct organic compounds containing the –CD3 functional group | Applied in anhydrous, oxygen-free Grignard reactions to achieve highly selective deuteromethylation |
| Analytical Chemistry | Used as an isotopically labeled standard or internal standard to support mass spectrometry or NMR analysis | Enables reaction pathway tracing or quantitative analysis of target compounds through precise incorporation of the –CD3 group |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (MgI2-CD3 content) | Titration with standardized Na2S2O3 solution | Iodide is oxidized to iodine by excess KIO3/KI under acidic conditions, then back-titrated with thiosulfate using starch indicator. |
| Moisture content | Karl Fischer titration | Electrochemical reaction between iodine, sulfur dioxide, water, and base in methanol medium quantifies water content. |
| Residual solvent (THF, diethyl ether) | Gas chromatography (GC-FID) | Volatile solvents are separated on a capillary column and detected by flame ionization. |
| Heavy metals (Pb, Cd, Hg, As) | ICP-MS | Elements are atomized and ionized in plasma, then quantified by mass-to-charge ratio detection. |
| Chloride impurity | Ion chromatography (IC) | Chloride ions are separated on an anion-exchange column and detected by suppressed conductivity. |
| Magnesium content | Complexometric titration with EDTA | Mg2+ forms stable complex with EDTA at pH 10; endpoint detected with Eriochrome Black T indicator. |
| Deuterium enrichment (D%) | NMR spectroscopy (1H NMR in CDCl3) | Ratio of residual CH3 vs CD3 proton signal integrals determines isotopic purity. |
| Acidic impurities (HI, Mg(OH)I) | Acid-base potentiometric titration | Total titratable acidity neutralized with standardized NaOH; endpoint determined by pH inflection. |
| Particulate matter | Light obscuration particle count | Particles in solution scatter or block light beam; counts and sizes are measured per USP <788>. |
| Color | Visual comparison against APHA color standard | Solution color assessed in 100-mm cell against platinum-cobalt scale under controlled lighting. |
| Density | Digital density meter | Oscillation period of U-tube filled with sample correlates to density via calibrated relationship. |
| Stability-indicating impurities | HPLC-UV | Degradation products and structural analogs separated on reverse-phase C18 column and detected at 220 nm. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow solution in tetrahydrofuran |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Odor | Characteristic mild ether-like odor |
| Solubility | Miscible with THF, diethyl ether; insoluble in water |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.