China Factory Direct
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| CAS number | 41252-95-3 |
| Product name | 1-CHLORO-4-IODO-2-NITROBENZENE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Used in the synthesis of quinolone antibacterial agents (e.g., gatifloxacin) and other iodine-containing drug molecules, leveraging iodine’s reactivity in coupling reactions. |
| Agrochemicals | Agrochemical Intermediates | Used in the synthesis of nitro-substituted benzenoid agrochemicals, serving as a key scaffold for iodine incorporation. |
| Organic Synthesis | Coupling Reagent | Employed as a coupling partner in Suzuki, Sonogashira, or Heck reactions, where iodine acts as a reactive leaving group to construct complex aromatic derivatives. |
| Materials Chemistry | Functional Material Monomer | Used in the synthesis of organic materials with tailored optoelectronic properties, via structural modification of the benzene ring to tune material performance. |
| Scientific Research | Building Block | Serves as an organic synthesis building block for developing novel heterocyclic compounds or for screening and synthesizing bioactive molecules. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration measuring water content based on iodine consumption in pyridine-methanol solvent system. |
| Heavy Metals | ICP-OES | Multi-element trace metal analysis via inductively coupled plasma optical emission spectroscopy after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection. |
| Iodine Content | Potentiometric Titration with Sodium Thiosulfate | Oxidative dissolution followed by iodometric back-titration to determine total iodine content. |
| Nitro Group Content | Reduction Titration (Zn/HCl) | Reduction of nitro group to phenylhydroxylamine followed by acid-base titration of liberated HCl. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>. |
| Organic Volatile Impurities | GC-MS | Screening and semi-quantitative identification of unknown volatile impurities using mass spectral library matching. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on Mie scattering theory. |
| Acid-Base Impurities | Non-aqueous Titration | Titration in glacial acetic acid medium using perchloric acid to quantify basic impurities. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue after controlled high-temperature ashing at 600 C. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124–128°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.