Z-DL-ALA-OH Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 4132-86-9 |
| Product name | Z-DL-ALA-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Z-DL-ALA-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-DL-ALA-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-DL-ALA-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral intermediate in the synthesis of β-lactam antibiotics, antiviral agents, and other active pharmaceutical ingredients (APIs) containing an alanine moiety | Introduced via solid-phase or solution-phase peptide synthesis to construct peptide chains with defined stereochemistry; commonly employed for amino group protection, with the CBZ protecting group subsequently removed by hydrogenolysis or acidolysis |
| Peptide Synthesis | Used as an N-α-carbobenzyloxy (CBZ)-protected DL-alanine derivative to suppress side reactions and control stereochemistry | Employed as a building block in peptide coupling reactions to form peptide bonds with other amino acids; the CBZ group is cleaved post-reaction via catalytic hydrogenation |
| Organic Synthesis | Used as a chiral synthon or precursor for the preparation of non-natural amino acids and their derivatives | Participates in asymmetric synthesis, alkylation, or functional group transformation reactions to generate structurally diverse alanine analogues |
Manufacturing Quality Control of Z-DL-ALA-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase, with UV detection and calculation of enantiomeric excess. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection with standard calibration. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid sample against established visual reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 589 nm (Na D-line) to confirm identity and enantiomeric integrity. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., N-CBZ-glycine, deprotected alanine) using gradient HPLC with UV detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
Technical Specifications of Z-DL-ALA-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Optical Rotation | +/- 0.5° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Z-DL-ALA-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-DL-ALA-OH
Packaging of Z-DL-ALA-OH
Industrial Z-DL-ALA-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply