China Factory Direct
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| CAS number | 41404-58-4 |
| Product name | 2-Bromo-5-fluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of multiple pharmaceuticals | Converted into target compounds via substitution and coupling reactions |
| Pesticides | Used in the research and production of novel pesticides | Novel pesticide molecules with specific biological activity are developed through halogen exchange or cross-coupling reactions |
| Chemical Feedstocks | Key raw material for organic synthesis | Participates in various organic synthesis reactions—including Suzuki coupling and Heck reactions—to construct complex organic structures |
| Materials Science | Explored for applications in optoelectronic materials | Structural modification enables evaluation of its potential in luminescent materials and conductive polymers |
| Fine Chemicals | Precursor to functional chemicals | Selectively transformed in the presence of catalysts to produce functional chemicals with specialized properties |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/water as the mobile phase and a UV detector (e.g., 254 nm). Effectively separates the main component from impurities, enabling quantitative purity analysis. This is the most commonly used method in quality control. |
| Impurity Testing | Gas Chromatography (GC) | Employs a capillary column (e.g., DB-5MS), temperature programming, and a flame ionization detector (FID). Suitable for qualitative and quantitative analysis of volatile impurities, especially residual solvents and by-products, with high sensitivity. |
| Residual Solvent Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Combines the separation capability of gas chromatography with the identification power of mass spectrometry, enabling accurate identification and quantification of trace organic solvents (e.g., ethanol, acetone, dichloromethane), compliant with ICH Q3A/Q3B guidelines. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide molecular structural information, confirming the positions of bromine and fluorine substitution and verifying the correctness of the compound's structure. Commonly used in research and development stages and for reference standard comparison. |
| Molecular Weight Determination | Mass Spectrometry (MS) | Utilizes electrospray ionization (ESI) or electron ionization (EI) techniques to obtain the precise molecular ion peak ([M]⁺), assisting in confirming molecular weight and fragment characteristics, supporting structural identification. |
| Assay | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Leverages the characteristic absorption of 2-bromo-5-fluoropyridine at a specific wavelength (e.g., 260–270 nm) for content determination via a standard curve method. Simple and convenient, suitable for rapid screening. |
| Moisture Content Testing | Karl Fischer Titration (KF) | Used to determine moisture content in samples, suitable for hygroscopic materials or active pharmaceutical ingredients containing water of crystallization. Provides accurate results and is the standard method for moisture control. |
| Melting Point Determination | Micro Melting Point Apparatus | Determines the melting point range by observing the sample's melting process. Serves as an initial physical quality control parameter, helpful for assessing purity and consistency of the substance. |
| Test Item | Specification |
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| Appearance | White to light yellow powder or lumps |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 42–46°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.