China Factory Direct
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| CAS number | 4144-02-9 |
| Product name | O-METHYL-L-THREONINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of antibiotic and peptide-based drug intermediates | Used as a chiral building block for structural modification of β-lactam antibiotics |
| Biochemistry | Studying protein and enzyme structure and function | Applied in solid-phase peptide synthesis (SPPS) to incorporate specific methylated threonine residues |
| Organic Synthesis | Chiral compound synthesis feedstock | Employed in asymmetric synthesis reactions to construct complex molecular frameworks |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 205 nm, comparing peak area to a certified reference standard. |
| Optical Rotation | [alpha]D | Measurement of specific rotation using a digital polarimeter at 20 degrees C and sodium D-line (589 nm) in aqueous solution. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water based on stoichiometric reaction. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 degrees C, then weighing the non-volatile inorganic residue after cooling in a desiccator. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals by plasma excitation and optical emission detection. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities (e.g., L-threonine, O-methyl-D-threonine) using gradient HPLC. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated pH electrode in a 10 mg/mL aqueous solution at 25 degrees C. |
| Specific Optical Rotation Purity | Comparison of [alpha]D value | Verification of enantiomeric purity by confirming measured [alpha]D falls within +/- 5% of the literature value for pure O-methyl-L-threonine. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss determination after drying at 105 degrees C under vacuum for 2 hours, expressed as percentage. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample with sulfuric acid followed by ashing at 700 degrees C and gravimetric determination of residual sulfate salts. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic mesophilic microorganisms via filtration, membrane transfer to agar, and colony counting after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C |
| Optical Rotation | -37.5 to -36.5° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.