China Factory Direct
|
|
| CAS number | 41838-46-4 |
| Product name | 1-Methylpiperidin-4-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis of drug intermediates | Used as a key intermediate in organic synthesis to construct biologically active molecular frameworks; applied in the development of antidepressants, neuromodulators, and other pharmaceuticals |
| Chemical Research | Organic synthesis reagent | Applied in laboratory-scale construction of nitrogen-containing heterocycles; employed in fine chemical synthesis steps including coupling and acylation reactions |
| Pharmaceutical Manufacturing | Active pharmaceutical ingredient (API) synthesis | Used as a piperidine derivative precursor in specific drug manufacturing processes to introduce methyl and amino functional groups, thereby optimizing pharmacokinetic properties |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, condition, and presence of visible impurities under natural light or standard light source. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase column (e.g., C18) and UV detector (typically at 210–230 nm wavelength), calculate the content of the main component by comparing with reference standards. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate and detect organic impurities in raw materials using a gradient elution program; usually report individual impurities and total impurities. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) used in the production process according to ICH guidelines, using an FID detector. |
| Moisture | Karl Fischer Titration | Precisely determine moisture content in the sample, suitable for hygroscopic compounds; divided into volumetric and coulometric methods. |
| Melting Point | Melting Point Apparatus Method | Determine the temperature range at which the compound transitions from solid to liquid using automatic or manual melting point apparatus, used for identification and purity assessment. |
| pH Value (if in solution) | pH Meter Measurement | Prepare a water solution of the sample at a certain concentration and measure its acidity or alkalinity using a calibrated pH meter. |
| Enantiomeric Purity (if applicable) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Separate enantiomers using a chiral column and assess optical purity, applicable when enantiomeric impurities may be present. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | Weigh the residual inorganic matter after high-temperature incineration and sulfuric acid treatment of the sample to evaluate inorganic impurity content. |
| Heavy Metals | Thioacetamide Method (Pharmacopoeia Method) or ICP-MS | Detect heavy metal residues such as lead, cadmium, and mercury using colorimetry or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) after digestion. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic amine-like odor |
| Refractive Index (n20/D) | 1.465–1.475 |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.