PHT-ALA-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4192-28-3 |
| Product name | PHT-ALA-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for PHT-ALA-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk PHT-ALA-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of PHT-ALA-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antitumor agents (e.g., cytarabine derivatives) and protease inhibitors | Applied as a chiral protecting group; introduced into target molecules via amide bond coupling, then cleaved under basic or acidic conditions |
| Organic Synthesis | Employed as a chiral auxiliary in asymmetric alkylation, allylation, and related reactions | Condensed with aldehydes or ketones to form imines, enabling stereoselective addition; alternatively used as a substrate for asymmetric α-functionalization |
| Analytical Chemistry | Used as a modifying ligand for chiral stationary phases in chromatography columns | Reacted with silanol groups on silica gel surfaces via carboxyl-group condensation of N-phthaloyl-L-alanine to construct chiral recognition sites |
Manufacturing Quality Control of PHT-ALA-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and control based on relative retention times and threshold limits. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water content based on stoichiometric reaction with iodine and sulfur dioxide. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 700-800 C to volatilize organic matter, then weighing inorganic residue as sulfate ash. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, using plasma emission spectroscopy with element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separation and quantification of sulfate ions using anion-exchange column and conductivity detection. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light (589 nm) to confirm chiral integrity and enantiomeric purity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to obtain D10, D50, D90 values based on Mie theory. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic bacteria and fungi by filtration, membrane transfer to selective media, and colony counting after incubation. |
| Residual Solvents | GC-FID | Quantification of residual solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
Technical Specifications of PHT-ALA-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -24.0 to -23.0° (c=1, in DMF) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of PHT-ALA-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of PHT-ALA-OH
Packaging of PHT-ALA-OH
Industrial PHT-ALA-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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