China Factory Direct
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| CAS number | 4214-73-7 |
| Product name | 2-Amino-5-cyanopyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeElectronic GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of insecticidal intermediates | Coupled with pyridine derivatives via cyanation, followed by amination and cyanation steps |
| Pharmaceuticals | Synthesis of anticancer drugs and antibiotic intermediates | Serves as a heterocyclic core in multi-step syntheses to construct pharmacologically active molecules |
| High-performance polymers | Synthesis of functionalized polymer monomers | Introduces cyano and amino functional groups via free-radical polymerization or condensation polymerization to enhance material performance |
| Organic synthesis | General-purpose organic synthesis intermediate | Used to construct complex heterocyclic compounds and participates in nucleophilic substitution and coupling reactions |
| Photosensitive materials | Preparation of photosensitizers or components of photosensitive resins | Acts as a nitrogen-containing heterocyclic component to improve photoresponsiveness and stability |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities (e.g., 2-amino-5-formylpyridine, unreacted 2-amino-5-bromopyridine) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Quantification of volatile organic solvents (e.g., DMF, toluene, methanol) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation; stoichiometric reaction with water in anhydrous pyridine/methanol medium. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of trace metals (Pb, Cd, Ni, Fe) after acid digestion, based on element-specific atomic emission intensities. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid–liquid phase transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Assessment of physical state (crystalline powder) and color intensity against APHA standards in solution (e.g., 1% w/v in ethanol). |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of inorganic residue mass after charring at 700–800 °C, indicating inorganic ash content. |
| pH (1% aqueous suspension) | pH Meter | Measurement of aqueous slurry pH using calibrated electrode; reflects acidic/basic impurities or hydrolysis products. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on angular scattering intensity of laser light. |
| Bulk Density | ASTM D1895 Method A | Determination of mass per unit volume for freely settled powder using standardized cylinder and funnel apparatus. |
| Organic Volatile Impurities (e.g., cyanide precursors) | GC-MS | Targeted screening and confirmation of low-level volatile nitriles or amides using gas chromatography coupled with mass spectrometry. |
| Sulfated Ash | Gravimetric Analysis | Quantification of sulfate-derived inorganic residue after ignition following sulfuric acid treatment, per USP <281>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 124.0–128.0°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.