China Factory Direct
|
|
| CAS number | 421552-12-7 |
| Product name | 2-cyano-5-fluorobenzylbroMide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Constructing fluorinated aromatic heterocyclic structures via nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Intermediate for synthesizing fluorinated pyrethroids or novel insecticides | Introducing biologically active functional groups through nitrile transformation (e.g., hydrolysis to carboxylic acid, reduction to amine) or arene functionalization |
| Organic Synthesis | Multifunctional synthon for constructing complex fluorinated aromatic compounds | Alkylation using the benzylic bromide; cyclization or functional group conversion (e.g., to tetrazole) involving the nitrile group |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, state (e.g., colorless to pale yellow liquid), turbidity, or presence of impurities and precipitates with the naked eye. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with a UV detector (e.g., 220 nm or 254 nm). The main component content is calculated by peak area normalization. |
| Content Determination | Gas Chromatography (GC) or HPLC | GC is suitable for volatile samples, using an FID detector; HPLC is more commonly used for quantitative analysis of halogenated and cyanide compounds. |
| Moisture Content | Karl Fischer Titration | This method uses KF reagent to react with moisture in the sample. The moisture content is accurately determined by potentiometric or coulometric titration, ensuring product stability. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Combine headspace sampling with GC-FID to detect residual organic solvents (e.g., dichloromethane, toluene) from synthesis or purification processes. |
| Related Substances/Impurities | HPLC or GC-MS | HPLC is used to separate and detect process impurities and degradation products; GC-MS can be used for preliminary structural identification of unknown impurities. |
| Bromine Content | Potentiometric Titration or Ion Chromatography (IC) | Potentiometric titration uses silver nitrate standard solution to titrate bromide ions; ion chromatography directly measures free or hydrolyzed Br⁻. |
| pH Value (if prepared as a solution) | pH Meter Measurement | Dissolve the sample in an appropriate solvent (e.g., water/ethanol mixture) and measure its acidity or alkalinity using a calibrated pH meter to assess hydrolysis tendency. |
| Melting Point/Boiling Point | Melting Point Apparatus or Boiling Point Apparatus | Although it is a liquid, the boiling point or refractive index can be used to assess purity; high-purity samples have a narrow boiling range. |
| Refractive Index | Abe Refractometer | Measure the refractive index at a specific temperature as a physical constant for rapid identification and initial purity screening. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 75–79 °C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.