(2-Chloro-3-pyridinyl)methanol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 42330-59-6 |
| Product name | (2-Chloro-3-pyridinyl)methanol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (2-Chloro-3-pyridinyl)methanol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (2-Chloro-3-pyridinyl)methanol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (2-Chloro-3-pyridinyl)methanol
| Industry | Application | Process |
|---|---|---|
| Agrochemicals | Acetamiprid intermediate Key intermediate for synthesizing the neonicotinoid insecticide acetamiprid. |
Serves as a pyridine ring building block; undergoes sequential chlorination, nitration, and condensation to produce N-((6-chloro-3-pyridyl)methyl)-N-ethyl-N'-methyl-2-nitroethenamine (acetamiprid precursor). |
| Agrochemicals | Imidacloprid intermediate Used in synthesizing the neonicotinoid insecticide imidacloprid. |
Leverages reactive chlorine and hydroxymethyl groups to generate 2-chloro-5-(chloromethyl)pyridine (CCMP) via functional group transformation, followed by reaction with imidazolidine to yield imidacloprid. |
| Pharmaceuticals | Pharmaceutical building block Used to synthesize physiologically active drug molecules. |
Enables diverse chemical transformations—including nucleophilic substitution, oxidation, and esterification—on the pyridine ring chlorine and side-chain hydroxymethyl group to construct core scaffolds of drug candidates. |
| Organic synthesis | Fine chemical synthesis reagent Multifunctional synthon for preparing other pyridine derivatives. |
Oxidized to 2-chloro-3-pyridinecarboxaldehyde or carboxylic acid; subjected to nucleophilic substitution to introduce additional functional groups for constructing complex heterocyclic compounds. |
Manufacturing Quality Control of (2-Chloro-3-pyridinyl)methanol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching with reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, dichloromethane) against calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via electrochemical endpoint detection. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of Pb, Cd, Hg, As, and other regulated metals at sub-ppb levels. |
| Chloride Ion | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection after anion-exchange column separation. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a digital polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Heating sample to 600-700 C in platinum crucible, then weighing inorganic residue after cooling in desiccator. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Direct measurement using calibrated pH meter with glass electrode in a saturated aqueous suspension (10 mg/mL). |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard white background under controlled lighting per EP 2.2.1. |
| Particle Size Distribution | Laser Diffraction | Dry dispersion followed by size analysis using laser diffraction principle to determine D10, D50, D90 values. |
Technical Specifications of (2-Chloro-3-pyridinyl)methanol
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 62–66°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (2-Chloro-3-pyridinyl)methanol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of (2-Chloro-3-pyridinyl)methanol
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of (2-Chloro-3-pyridinyl)methanol
Industrial (2-Chloro-3-pyridinyl)methanol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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