L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 42438-90-4 |
| Product name | L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical Intermediates | Used to synthesize bioactive indole derivatives as precursors for antidepressant and antipsychotic drugs |
| Chemical Research | Organic Synthesis Reagent | Employed in laboratories as a chiral building block for asymmetric synthesis reactions |
| Biopharmaceuticals | Neurological Disease Research | Applied in studying the biological activity and pharmacological effects of compounds related to tryptophan metabolism |
Manufacturing Quality Control of L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220-280 nm based on peak area comparison to reference standard. |
| Chiral Purity | Chiral HPLC | Measures enantiomeric excess by separating (R)- and (S)-enantiomers on a chiral stationary phase with UV detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generated electrochemically or added reagent. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, ethyl acetate) by gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after ignition with sulfuric acid treatment and high-temperature incineration, followed by weighing. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection against reference standards or threshold limits. |
| Optical Rotation | Polarimetry | Measures specific rotation at specified wavelength (e.g., 589 nm) and temperature to confirm chiral identity and batch consistency. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| pH of Aqueous Suspension | pH Meter | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per EP 2.2.3. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension using Mie scattering theory and laser diffraction instrumentation. |
Technical Specifications of L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -31.0 to -29.0° (c=1, in methanol) |
| Melting Point | 184–188°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Safety Information of L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID
Industrial L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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