tert-Butyl carbamate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4248-19-5 |
| Product name | tert-Butyl carbamate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-Butyl carbamate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-Butyl carbamate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-Butyl carbamate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Amino acid and peptide protecting agent | Selectively protects amino groups via its tert-butoxycarbonyl (Boc) group, applied in nucleophilic substitution or condensation reactions to protect the N-terminus. |
| Pharmaceuticals | Active pharmaceutical ingredient (API) intermediate synthesis | Used in the synthesis of complex drug molecules; functional group transformations are achieved by acid-catalyzed deprotection. |
| Chemicals | Organic synthesis intermediate | Reacted with primary amines to form N-Boc derivatives during tertiary amine preparation; final products are obtained via hydrogenation or cleavage. |
| Chemicals | Peptide synthesis | Temporarily protects amino acid side-chain or backbone amino groups in solid-phase or solution-phase peptide synthesis. |
Manufacturing Quality Control of tert-Butyl carbamate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water in the sample. |
| Residual Solvents (e.g., THF, Hexane) | Gas Chromatography (GC) with FID or MS detection | Separation and quantification of volatile organic impurities using headspace or direct injection with internal standard calibration. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Atomization and excitation of metals in argon plasma; quantification via element-specific emission line intensity. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column followed by quantitative detection based on electrical conductivity. |
| Acid Value | Acid-Base Titration (NaOH in methanol) | Neutralization of acidic impurities with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified criteria under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C in a muffle furnace. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using reversed-phase C18 column and UV absorbance at 210 nm. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compounds in solution at specified concentration and path length. |
| Bulk Density | ASTM D1895 Method A (Tapped Density Tester) | Determination of mass per unit volume after mechanical tapping to achieve reproducible packing density. |
Technical Specifications of tert-Butyl carbamate
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 52–56°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-Butyl carbamate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of tert-Butyl carbamate
Packaging of tert-Butyl carbamate
Industrial tert-Butyl carbamate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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