2,2',4'-Trichloroacetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4252-78-2 |
| Product name | 2,2',4'-Trichloroacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,2',4'-Trichloroacetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,2',4'-Trichloroacetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,2',4'-Trichloroacetophenone
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the organophosphorus insecticide chlorpyrifos | Condensed with sodium trichloropyridinol to produce technical-grade chlorpyrifos |
| Pharmaceuticals | Preceding intermediate in the synthesis of the antifungal agent clotrimazole | Further converted into the clotrimazole structural unit via Grignard reaction or amination |
| Dyes | Synthesis intermediate for azo dyes and triarylmethane dyes | Participates in diazotization-coupling reactions or serves as an acylating agent to introduce the chloroacetophenone moiety |
Manufacturing Quality Control of 2,2',4'-Trichloroacetophenone
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reverse-phase C18 column and a UV detector (e.g., 254 nm), with external standard or area normalization method for quantification. Suitable for accurately determining the content of the main component and major impurity levels in the sample. |
| Assay | Gas Chromatography (GC) | Employs a capillary column (e.g., DB-5) and FID detector, using internal standard method for quantification. Applicable for assay analysis of volatile and thermally stable organic compounds. Thermal decomposition at high temperatures should be considered. |
| Structural Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirms molecular structure consistency by comparing characteristic functional group absorption peaks (e.g., carbonyl C=O around 1680 cm⁻¹, aromatic rings and C-Cl bonds) with reference spectra. |
| Impurity Analysis | Liquid Chromatography-Mass Spectrometry (LC-MS) | After HPLC separation, impurities are detected by mass spectrometry, enabling identification of unknown impurity structures with high sensitivity and selectivity. Used for qualitative and semi-quantitative analysis of trace impurities. |
| Residual Solvent Testing | Headspace Gas Chromatography (HS-GC) | The sample is sealed and heated; volatile solvents enter the headspace and are analyzed by GC-FID or GC-MS. Complies with ICH Q3C guidelines, suitable for monitoring common residual solvents such as methanol and ethyl acetate. |
| Loss on Drying / Moisture Content | Karl Fischer Titration | Determines trace moisture in samples using coulometric or volumetric methods to ensure product stability during storage and prevent hydrolysis-related side reactions. |
| Melting Point Determination | Capillary Melting Point Apparatus | Measures the temperature range at which a substance transitions from solid to liquid. Serves as a physical constant to assist in assessing purity and batch-to-batch consistency. Typical melting point range is approximately 70–75°C (literature value). |
| Appearance and Color | Visual Color Comparison Method | Visually examines the solid's color (should be white to off-white crystals) under standard lighting conditions and compares it with standard color solutions to evaluate abnormal discoloration or contamination. |
Technical Specifications of 2,2',4'-Trichloroacetophenone
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 74.0–77.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,2',4'-Trichloroacetophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,2',4'-Trichloroacetophenone
Packaging of 2,2',4'-Trichloroacetophenone
Industrial 2,2',4'-Trichloroacetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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