2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 425378-68-3 |
| Product name | 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a key intermediate in synthesizing fluorinated nitro-aryl candidate drug molecules, particularly kinase inhibitors and antitumor compounds | Suzuki-Miyaura cross-coupling with aryl halides under palladium catalysis (e.g., Pd(dppf)Cl₂) to construct C–C bonds |
| Agrochemical R&D | Serves as a structural building block for novel fluorinated heterocyclic insecticides and fungicides | Palladium-catalyzed coupling with heterocyclic halides, followed by nitro group reduction, cyclization, or functional group transformation |
| Materials Science | Functions as a building block for electron-transport layer materials in organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs) | Suzuki coupling to introduce boronate ester moieties, followed by polymerization or coupling with conjugated units such as bromofluorene or carbazole to tune HOMO/LUMO energy levels |
Manufacturing Quality Control of 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by comparing retention times and peak areas to qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection against calibration curves. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg) by plasma ionization followed by mass spectrometric detection of elemental isotopes. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by precise weighing of residual non-volatile material. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid phase using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established reference samples. |
| Bulk Density | USP <616> Tapped Density Test | Measures mass per unit volume after mechanical tapping to assess powder flow and packing characteristics. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution by analyzing angular scattering pattern of laser beam passing through dispersed sample. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral integrity and absence of racemization. |
Technical Specifications of 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
Safety Information of 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER
Industrial 2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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