China Factory Direct
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| CAS number | 4271-30-1 |
| Product name | N-(p-Aminobenzoyl)glutamic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for folic acid (vitamin B9) and its derivatives | Condensed with pteridine compounds for chemical synthesis of folic acid or analogues (e.g., methotrexate) |
| Pharmaceuticals | Key precursor in anticancer drug development | Used in multistep organic synthesis to construct core structures of antimetabolite anticancer agents |
| Biochemistry | Substrate or inhibitor in enzymology studies | Employed to assay activity of folate metabolism–related enzymes, such as dihydrofolate reductase (DHFR) |
| Analytical Chemistry | Reference standard or control substance | Used as a qualitative and quantitative reference for folate metabolites in high-performance liquid chromatography (HPLC) or mass spectrometry analysis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using HPLC coupled with diode-array detection, with identification and quantification against reference standards or threshold limits. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of trace heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions using anion-exchange column and eluent gradient. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue after treatment with sulfuric acid. |
| Optical Rotation | [alpha]D Measurement | Polarimetric determination of specific optical rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| pH of Solution | Potentiometric Titration | Measurement of pH in aqueous suspension or solution using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using laser scattering to determine volume-based particle size distribution. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition temperature range using calibrated capillary method per USP/EP guidelines. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens using membrane filtration and culture media incubation. |
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-250°C |
| Optical Rotation | -13.0 to -17.0° (c=1, 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.