4-Chloro-3-iodobenzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 42860-04-8 |
| Product name | 4-Chloro-3-iodobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Chloro-3-iodobenzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Chloro-3-iodobenzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Chloro-3-iodobenzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Introduces aryl or alkynyl groups via Suzuki coupling, Sonogashira coupling, or other palladium-catalyzed cross-coupling reactions |
| Agrochemicals | Synthesis of herbicides or fungicides with specific biological activity | Serves as a starting material for aromatic ring substitution modification, participating in nucleophilic substitution or metal-catalyzed coupling reactions |
| Materials Science | Preparation of organic optoelectronic materials (e.g., functional molecules for OLEDs and OFETs) | Constructs conjugated backbones through multistep organic synthesis; iodine and carboxylic acid functional groups enable directed functionalization |
| Chemical Research | Used as an organic building block for constructing complex aromatic compounds | The carboxy group can be converted to acyl chloride, ester, or amide; the iodine atom enables further functional group transformations (e.g., halogen exchange, metallation) |
Manufacturing Quality Control of 4-Chloro-3-iodobenzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., 4-chlorobenzoic acid, 3-iodobenzoic acid) via gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate, toluene) using gas chromatography with flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Determines water content by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Ion Impurity | Ion Chromatography | Separates and quantifies chloride anions using suppressed conductivity detection after aqueous extraction. |
| Iodide Ion Impurity | Ion Chromatography | Separates and quantifies iodide anions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric (Thermogravimetric) | Measures mass loss after drying under controlled temperature and vacuum, indicating volatile matter and residual solvents. |
| Residue on Ignition | Sulfated Ash Test | Quantifies inorganic residue after high-temperature ignition (700-800 C) following sulfuric acid treatment. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in suspension using Mie scattering theory and a laser diffraction particle analyzer. |
| pH of Aqueous Suspension | pH Meter | Determines pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
Technical Specifications of 4-Chloro-3-iodobenzoic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 175–179°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Chloro-3-iodobenzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Chloro-3-iodobenzoic acid
Packaging of 4-Chloro-3-iodobenzoic acid
Industrial 4-Chloro-3-iodobenzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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