China Factory Direct
|
|
| CAS number | 43039-98-1 |
| Product name | 2-PROPIONYLTHIAZOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate, used as the side-chain building block in cephalosporin antibiotic synthesis (e.g., cefixime) | Produced via acylation of 2-aminothiazole with propionyl chloride under basic conditions |
| Agrochemicals | Fungicide intermediate, used in the synthesis of thiazole-based agricultural fungicides | Employed as a key heterocyclic fragment in coupling reactions to construct the active molecular scaffold |
| Materials Science | Functional dopant in the electron-transport layer of organic light-emitting diode (OLED) devices | Incorporated at 1–5 wt% into host materials (e.g., TPBi) via vacuum thermal evaporation or solution spin-coating |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Properties | Visual Inspection, Melting Point Determination | Observe color and physical state (typically colorless to pale yellow liquid or low-melting solid); determine melting point range as an initial indicator of purity. |
| Purity (Main Component Content) | Gas Chromatography (GC) | Use capillary column (e.g., DB-5 or HP-5), FID detector, internal standard method or area normalization for quantification; suitable for analysis of volatile components. |
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Use C18 column, UV detector (220–254 nm), mobile phase with gradient elution of methanol-water or acetonitrile-water; suitable for detecting thermally unstable or non-volatile impurities. |
| Impurity Profiling | GC-MS or HPLC-MS | Hyphenated mass spectrometry techniques for structural identification of unknown impurities, such as unreacted starting materials (thiazole), by-products (e.g., 2-acetylthiazole), and degradation products. |
| Water Content | Karl Fischer Titration | For trace moisture determination; ensures sample dryness to prevent hydrolysis or catalytic side reactions; accuracy reaches ppm level. |
| Residual Solvents | GC-MS or Headspace GC | Detect solvents used during synthesis (e.g., ethanol, ethyl acetate, dichloromethane), complying with ICH Q3C guidelines. |
| Sulfur Element Confirmation | Elemental Analysis (EA) or ICP-MS | Confirm elemental ratios (C, H, N, S) matching theoretical values (C₆H₇OS: C 60.0%, H 5.9%, S 16.8%) via elemental analysis, or detect metal impurities using ICP-MS. |
| Infrared Spectroscopy (Structure Confirmation) | Fourier Transform Infrared Spectroscopy (FT-IR) | Identify characteristic functional groups: carbonyl C=O stretching vibration (~1680 cm⁻¹), thiazole ring skeleton vibrations (~1500–1600 cm⁻¹). |
| Nuclear Magnetic Resonance (Structure Confirmation) | ¹H NMR and ¹³C NMR | Measured in CDCl₃, confirm chemical shifts of thiazole ring protons (δ 7.5–8.0 ppm), propionyl –CH₂– (δ ~2.8 ppm), and –CH₃ (δ ~1.1 ppm) for structure confirmation and auxiliary purity assessment. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | -15 to -10°C |
| Refractive Index (n20/D) | 1.525–1.535 |
| Odor | Characteristic thiazole odor |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.